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年轻人的冲动性自杀企图-瑞典一项前瞻性多中心队列研究。

Impulsive suicide attempts among young people-A prospective multicentre cohort study in Sweden.

机构信息

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Stockholm City Council, St. Goran, SE-112 61, Stockholm.

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Stockholm City Council, St. Goran, SE-112 61, Stockholm.

出版信息

J Affect Disord. 2019 Jan 15;243:421-426. doi: 10.1016/j.jad.2018.09.070. Epub 2018 Sep 17.

Abstract

BACKGROUND

We aimed to compare the prevalence of impulsive suicide attempts (ISA) among young adults and those over 25 who present at hospital in connection with attempted suicide. We also aimed to identify factors associated with ISA in young adults and to assess medical severity as well as the probability of repeated suicide attempts in this age group.

METHOD

A prospective multicentre cohort study included hospital known cases of suicide attempt (N = 666). The prevalence of ISA was compared between young adults (18-25) and adults aged > 26. We used logistic regression models to identify factors associated with ISA, associations of ISA with high medical severity and prediction of new fatal or non-fatal suicide attempts within 6 months.

RESULTS

43.7% of the young patients had made an ISA, and 30.2% among those aged > 26 (p = 0.001). Among the young, substance use disorder was associated with ISA; crude odds ratio (OR) 2.0 (1.0-4.2), and adjusted OR 2.1 (0.99-4.4). Affective disorder and unemployment/ sickness absence implied lower odds of ISA. ISA resulted in injuries of high medical severity as often as more planned attempts and non-fatal or fatal repetition within 6 months was equally common (30%) in both groups.

LIMITATIONS

The study was set in psychiatric emergency services, which limits the generalizability.

CONCLUSIONS

Clinicians should acknowledge that suicide attempts among youth often occur without previous planning and may result in medically severe injuries. The probability of new fatal or non-fatal suicide attempts should be kept in mind also after an impulsive suicide attempt.

摘要

背景

本研究旨在比较年轻成人(18-25 岁)和 26 岁以上因自杀未遂就诊于医院的患者中冲动性自杀企图(ISA)的发生率。我们还旨在确定年轻成人中与 ISA 相关的因素,并评估该年龄段的医疗严重程度以及重复自杀企图的可能性。

方法

本前瞻性多中心队列研究纳入了 666 例医院已知的自杀企图病例。比较了年轻成人(18-25 岁)和 26 岁以上成年人之间 ISA 的发生率。我们使用逻辑回归模型来确定与 ISA 相关的因素,ISA 与高医疗严重程度的关联以及 6 个月内新发致命或非致命自杀企图的预测。

结果

43.7%的年轻患者发生了 ISA,而 26 岁以上患者中这一比例为 30.2%(p=0.001)。在年轻人中,物质使用障碍与 ISA 相关;未经调整的比值比(OR)为 2.0(1.0-4.2),调整后的 OR 为 2.1(0.99-4.4)。情感障碍和失业/病假与 ISA 的可能性降低相关。ISA 导致的医疗严重程度与更有计划的自杀一样常见,并且 6 个月内非致命或致命重复的情况在两组中同样常见(30%)。

局限性

该研究在精神科急诊服务中进行,这限制了其普遍性。

结论

临床医生应该认识到,年轻人的自杀企图常常是无事先计划的,可能导致严重的医疗损伤。在冲动性自杀企图后,也应该考虑新的致命或非致命自杀企图的可能性。

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