Department of Psychiatry and Neurochemistry, University of Gothenburg, Blå stråket 15, vån 3, SU/S, 413 45, Göteborg, Sweden.
Region Västra Götaland, Sahlgrenska University Hospital, Psychosis Clinic, Mölndal, Sweden.
BMC Psychiatry. 2022 Jun 24;22(1):428. doi: 10.1186/s12888-022-04057-0.
ADHD is common in psychiatric populations. This study aimed to compare clinical characteristics in adults with and without ADHD who presented with self-harm, and to compare later risk of suicidal behaviour within 6 months.
Eight hundred four adults presented with self-harm (with and without suicidal intent) at psychiatric emergency services at three Swedish hospitals. Persons with a discharge ICD-10 diagnosis F90.0-F90.9 or a prescription for ADHD medication were considered to have ADHD (n = 93). Medical records were reviewed for evidence of subsequent suicide attempts (SA) within 6 months; suicides were identified by national register.
Recent relationship problems were more prevalent in the ADHD group. While the index episodes of those with ADHD were more often non-suicidal, and actual SAs more often rated as impulsive, medical lethality at presentation did not differ in attempters with and without ADHD. Subsequent SAs (fatal or non-fatal) were observed in 29% of the ADHD group and 20% in all others (P = .005). A logistic regression model showed elevated risk of suicidal behaviour during follow-up in the ADHD group (OR = 1.70, CI 1.05-2.76), although a final regression model suggested that this association was partly explained by age and comorbid emotionally unstable personality disorder.
Findings highlight the need for clinicians to take self-harm seriously in adults with ADHD.
注意缺陷多动障碍(ADHD)在精神科人群中较为常见。本研究旨在比较有和无 ADHD 并伴有自伤的成年患者的临床特征,并比较 6 个月内自杀行为的后续风险。
804 名有自伤(有和无自杀意念)的成年人在瑞典三家医院的精神科急诊就诊。符合 ICD-10 诊断 F90.0-F90.9 或 ADHD 药物处方的患者被认为患有 ADHD(n=93)。对医疗记录进行了回顾,以确定 6 个月内随后自杀尝试(SA)的证据;通过国家登记处确定自杀事件。
ADHD 组近期的人际关系问题更为普遍。虽然 ADHD 组的首发事件多为非自杀性,实际的 SA 更常被评定为冲动性,但在有和无 ADHD 的尝试者中,就诊时的医疗致死率并无差异。ADHD 组有 29%的患者发生了随后的 SA(致命或非致命),而所有其他患者中有 20%(P=0.005)。logistic 回归模型显示,ADHD 组在随访期间自杀行为的风险增加(OR=1.70,CI 1.05-2.76),尽管最终回归模型表明,这种关联部分可以通过年龄和共患情绪不稳定人格障碍来解释。
研究结果强调了临床医生在治疗有 ADHD 的成年人时需要认真对待自伤行为。