Rabinovich R D, Lascano E F, Boxaca M C
Intervirology. 1986;25(4):216-22. doi: 10.1159/000149678.
The percentage of suckling mice that developed paralysis after intracerebral Junin virus (XJ-JV pathogenic strain) inoculation (13.8%) consistently increased after 5 serial passages of virus-infected brain or spinal cord obtained from paralytic animals, reaching 37.9 and 45.7%, respectively. As expected, all paralytic mice exhibited an identical spinal cord histologic picture, with widespread JV antigen in spinal cord astrocytes and neurons, particularly the large motor neurons of the anterior horn. These findings strongly support the existence of a motor neurotropic viral particle subpopulation in parental XJ-JV stock.
接种脑内胡宁病毒（XJ-JV致病株）后出现麻痹的乳鼠百分比（13.8%），在从麻痹动物获得的病毒感染脑或脊髓连续传代5次后持续增加，分别达到37.9%和45.7%。正如预期的那样，所有麻痹小鼠均表现出相同的脊髓组织学图像，脊髓星形胶质细胞和神经元中广泛存在JV抗原，尤其是前角的大型运动神经元。这些发现有力地支持了亲代XJ-JV毒株中存在运动嗜神经病毒粒子亚群。
