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寻常痤疮及其与饮食摄入的关联:马来西亚视角

Acne vulgaris and its association with dietary intake: a Malaysian perspective.

作者信息

Suppiah Thiribura Sundra Sumathi, Sundram Thavin Kumar Mathana, Tan Eugenie Sin Sing, Lee Chew Kek, Bustami Normina Ahmad, Tan Chung Keat

机构信息

School of Healthy Aging, Medical Aesthetics and Regenerative Medicine, Faculty of Medicine and Health Science, UCSI University, Kuala Lumpur, Malaysia.

出版信息

Asia Pac J Clin Nutr. 2018;27(5):1141-1145. doi: 10.6133/apjcn.072018.01.

Abstract

BACKGROUND AND OBJECTIVES

Acne vulgaris is a common skin condition among adolescents and young adults. Its relationship with the dietary intake is highly debatable and equivocal. This study aimed to identify the association between acne vulgaris and dietary intake among Malaysians.

METHODS AND STUDY DESIGN

A case-control study was conducted involving 57 acne vulgaris patients and 57 age-, gender- and ethnicity-matched controls. All participants were aged 14 and above. The Comprehensive Acne Severity Scale (CASS) was used to categorise patients (grades 2 to 5) and controls (grades 0 to 1). Information such as the demographics, family history, smoking habits and dietary intake were collected using a self-administered questionnaire.

RESULTS

In the patient arm, the gender ratio of male to female was 1.5:1. 43 patients (75.4%) had a family history of acne vulgaris. No significant association was found for acne in patients with a history of smoking. Milk consumption was significantly higher in patients (63.2%, n=36) versus controls (43.9%, n=25), (OR=2.19, p<0.05). In addition, chocolate consumption was also significantly higher in patients (43.9%, n=25) versus controls (24.6%, n=14), (OR=2.4, p<0.05). No significant association was found with the intakes of sweets, potatoes, chips, nuts, yoghurt, ice-cream or carbonated drinks.

CONCLUSIONS

Dietary intake of milk and chocolate may play a role in acne vulgaris. Prospective cohort and intervention studies are recommended to explore whether a causal relationship might obtain.

摘要

背景与目的

寻常痤疮是青少年和青年中常见的皮肤疾病。其与饮食摄入之间的关系极具争议且尚无定论。本研究旨在确定马来西亚人群中寻常痤疮与饮食摄入之间的关联。

方法与研究设计

开展了一项病例对照研究,纳入57例寻常痤疮患者以及57例年龄、性别和种族匹配的对照。所有参与者年龄均在14岁及以上。使用综合痤疮严重程度量表(CASS)对患者(2至5级)和对照(0至1级)进行分类。通过自行填写问卷收集人口统计学、家族史、吸烟习惯和饮食摄入等信息。

结果

在患者组中,男女比例为1.5:1。43例患者(75.4%)有寻常痤疮家族史。有吸烟史的患者中,痤疮与吸烟之间未发现显著关联。患者的牛奶摄入量(63.2%,n = 36)显著高于对照组(43.9%,n = 25),(比值比[OR]=2.19,p<0.05)。此外,患者的巧克力摄入量(43.9%,n = 25)也显著高于对照组(24.6%,n = 14),(OR = 2.4,p<0.05)。在甜食、土豆、薯片、坚果、酸奶、冰淇淋或碳酸饮料的摄入量方面未发现显著关联。

结论

牛奶和巧克力的饮食摄入可能在寻常痤疮中起作用。建议进行前瞻性队列研究和干预研究,以探讨是否可能存在因果关系。

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