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饮食与营养对寻常痤疮患者的影响。

Impact of Diet and Nutrition in Patients with Acne Vulgaris.

机构信息

Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.

Collegium Medicum-Faculty of Medicine, WSB University, 41-300 Dabrowa Gornicza, Poland.

出版信息

Nutrients. 2024 May 14;16(10):1476. doi: 10.3390/nu16101476.

Abstract

Acne vulgaris is a widespread a chronic inflammatory dermatosis that affects millions of people around the world, which has a significant influence on patients' standard of living. The progression of this dermatosis results in the appearance of inflammatory and non-inflammatory changes, and, in severe cases, disfiguring scars and hyperpigmentation. The aetiopathogenesis of acne is complex. It involves a complex interaction of many different factors, both endo- and exogenous in their effect on the hair and sebaceous unit. Genetic predisposition, hormones, the skin and gut microbiome, psychological stress, air pollutants, aggressive facial products, and certain medications are cited as factors influencing acne formation. The link between nutrition and acne is extensively debated for many years and is still relatively controversial. Diet is commonly recognised to have a direct relationship with certain biochemical markers and the transcription of genes related to sebaceous gland function, and the proliferation of bacteria and inflammation that encourage the progression of the disease. In this review, the authors take a closer look at the existing scientific reports on the involvement of nutrition in the development of acne vulgaris.

摘要

寻常痤疮是一种广泛存在的慢性炎症性皮肤病,影响着全世界数以百万计的人,对患者的生活质量有重大影响。这种皮肤病的发展导致出现炎症和非炎症性变化,在严重的情况下,会导致毁容性疤痕和色素沉着过度。痤疮的发病机制复杂,涉及许多不同因素的复杂相互作用,这些因素对内源性和外源性影响毛发和皮脂腺单位的作用。遗传易感性、激素、皮肤和肠道微生物组、心理压力、空气污染物、刺激性面部产品和某些药物被认为是影响痤疮形成的因素。多年来,营养与痤疮之间的联系一直存在广泛争议,目前仍然存在一定争议。人们普遍认为饮食与某些生化标志物以及与皮脂腺功能、细菌增殖和炎症相关的基因转录有直接关系,这些因素会促进疾病的发展。在这篇综述中,作者仔细研究了现有的关于营养在寻常痤疮发展中作用的科学报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05a0/11124289/29a8908179df/nutrients-16-01476-g001.jpg

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