Magazanik L G, Minenko M L
Neirofiziologiia. 1986;18(6):748-56.
Measurements of the synaptic delay of uniquantal responses have been made on frog cutaneous pectoris muscle. Extracellular focal recording and low mean quantal content (0.05-1) was used. The distribution of delays obtained had a polymodal character with the mean modal interval equal to 0.22 +/- 0.01 ms (n = 13). An increase of the quantal content induced only a redistribution of the mode weights, but the modal interval did not change. A decrease in the temperature induced an increase in the modal interval with the temperature coefficient Q10 = 2.42 +/- 0.14 (n = 15). According to the hypothesis which was used for explaining the data obtained, the process of transmitter quanta release is determined by interaction of two molecular mechanisms: an increase of the release probability depending on the intracellular calcium concentration; rhythmical work of the mechanism realizing the quantum release. The latter does not depend on the calcium concentration but depends on temperature. The polymodal distribution of synaptic delays reflects this rhythmical work of each presynaptic active zone.
已对蛙胸皮肌单量子反应的突触延迟进行了测量。采用细胞外局部记录法，且平均量子含量较低（0.05 - 1）。所获得的延迟分布具有多峰特征，平均模态间隔等于0.22 ± 0.01毫秒（n = 13）。量子含量的增加仅引起模态权重的重新分布，但模态间隔未改变。温度降低导致模态间隔增加，温度系数Q10 = 2.42 ± 0.14（n = 15）。根据用于解释所得数据的假设，递质量子释放过程由两种分子机制的相互作用决定：释放概率的增加取决于细胞内钙浓度；实现量子释放的机制的节律性活动。后者不依赖于钙浓度，但依赖于温度。突触延迟的多峰分布反映了每个突触前活动区的这种节律性活动。
