羊膜来源干细胞移植：一种治疗神经系统疾病的新方法。
Amnion-derived stem cell transplantation: A novel treatment for neurological disorders.
作者信息
Carvajal Horacio G, Suárez-Meade Paola, Borlongan Cesario V
机构信息
Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Florida, USA.
出版信息
Brain Circ. 2016 Jan-Mar;2(1):1-7. doi: 10.4103/2394-8108.178537. Epub 2016 Mar 11.
Abstract
In this review, we evaluated the literature reporting the use of amniotic stem cells (ASCs) in regenerative medicine for the treatment of neurological disorders. There is an increasing amount of evidence that indicates the exacerbation of the primary injury by inflammation in neurological disorders characterized by rampant inflammation, thereby increasing damage to the central nervous system (CNS). To address this, we focus on the amnion cells' anti-inflammatory properties, which make their transplantation a promising treatment for these disorders. In addition, we offered insights into new applications of the ASC in the fields of regenerative medicine and tissue engineering.
摘要
在本综述中，我们评估了有关羊膜干细胞（ASCs）在再生医学中用于治疗神经疾病的文献。越来越多的证据表明，在以炎症猖獗为特征的神经疾病中，炎症会加剧原发性损伤，从而增加对中枢神经系统（CNS）的损害。为了解决这一问题，我们关注羊膜细胞的抗炎特性，这使得其移植成为治疗这些疾病的一种有前景的方法。此外，我们还深入探讨了羊膜干细胞在再生医学和组织工程领域的新应用。
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