1 Global Center for Children and Families, UCLA Semel Institute for Neuroscience and Human Behavior, University of California , Los Angeles, Los Angeles, California.
2 Section of Infectious Diseases and Global Health, University of Chicago , Chicago, Illinois.
AIDS Patient Care STDS. 2018 Oct;32(10):399-407. doi: 10.1089/apc.2018.0066.
Women account for 25% of all people living with HIV and 19% of new diagnoses in the United States. African American (AA) women are disproportionately affected. Yet, differences in the care continuum entry are not well understood between patient populations and healthcare sites. We aim to examine gender differences in diagnosis and linkage to care (LTC) in the Expanded HIV Testing and Linkage to Care (X-TLC) program within healthcare settings. Data were collected from 14 sites on the South and West sides of Chicago. Multivariate logistic regression analysis was used to determine the differences in HIV diagnoses and LTC by gender and HIV status. From 2011 to 2016, X-TLC performed 281,017 HIV tests; 63.7% of those tested were women. Overall HIV seroprevalence was 0.57%, and nearly one third (29.4%) of HIV-positive patients identified were cisgender women. Of newly diagnosed HIV-positive women, 89% were AA. 58.5% of new diagnoses in women were made at acute care hospitals, with the remainder at community health centers. Women who were newly diagnosed had a higher baseline CD4 count at diagnosis compared with men. Overall, women had lower odds of LTC compared with men (adjusted odds ratio = 0.58, 95% confidence interval 0.44-0.78) when controlling for patient demographics and newly versus previously diagnosed HIV status. Thus, interventions that focus on optimizing entry into the care continuum for AA women need to be explored.
美国有 25%的 HIV 感染者和 19%的新增 HIV 感染者为女性,其中非裔美国女性受影响的程度尤为严重。然而,人们对于患者人群和医疗场所之间在护理连续体进入方面的差异还没有很好的了解。我们旨在检查在扩大的 HIV 检测和护理链接(X-TLC)计划中,医疗环境中诊断和与护理链接(LTC)方面的性别差异。数据来自芝加哥南部和西部的 14 个地点。使用多变量逻辑回归分析来确定性别和 HIV 状况对 HIV 诊断和 LTC 的差异。从 2011 年到 2016 年,X-TLC 进行了 281017 次 HIV 检测;接受检测的人中有 63.7%是女性。总体 HIV 血清流行率为 0.57%,近三分之一(29.4%)的 HIV 阳性患者是顺性别女性。新诊断的 HIV 阳性女性中,89%是非裔美国人。58.5%的新诊断女性是在急症护理医院做出的,其余的是在社区卫生中心。与男性相比,新诊断的 HIV 阳性女性在诊断时的 CD4 计数基线更高。总体而言,与男性相比,女性 LTC 的可能性较低(调整后的优势比=0.58,95%置信区间为 0.44-0.78),同时控制了患者人口统计学特征以及新诊断和以前诊断的 HIV 状态。因此,需要探索专注于优化非裔美国女性进入护理连续体的干预措施。