Philadelphia Department of Public Health, Division of Ambulatory Health Services, Pennsylvania, USA.
J Natl Med Assoc. 2012 Jan-Feb;104(1-2):14-9. doi: 10.1016/s0027-9684(15)30130-9.
This paper evaluates gender differences in CD4 cell counts at human immunodeficiency virus (HIV) diagnosis of an African-born population receiving care for HIV infection in a publicly financed clinic setting in Philadelphia, Pennsylvania, in comparison with a non-African, foreign-born cohort in the same setting.
Records of foreign-born individuals receiving HIV care at the Philadelphia city health centers between January 2007 and December 2008 were reviewed. Data abstracted included demographics, country of origin, reason for HIV testing, and baseline CD4 cell count. Associations among baseline CD4 cell count, demographic variables and reason for testing were assessed by gender and by world region of origin (African or non-African).
During the review period, 107 African patients and 127 non-African patients met inclusion criteria. Mean CD4 cell counts at diagnosis were 263 cells/mm3 for African men and 362 cells/mm3 for African women (p = .055). For other foreign-born individuals, mean CD4 cell counts did not vary by gender. African women were more likely than African men to undergo routine testing in the setting of reproductive health care, while there was no gender difference in rates of reproduction-related testing for non-Africans.
African men in Philadelphia are diagnosed with HIV at a later stage of disease than African women are. This difference is associated with higher rates of routine testing of African women in reproductive health care settings. Efforts to engage African men in the United States in routine HIV testing are urgently needed as part of the national "test and treat" strategy of HIV testing and linkage to care.
本研究评估了宾夕法尼亚州费城一家公共资助的诊所中,接受 HIV 感染治疗的非洲出生人群与同一环境中的非非洲出生的外国出生人群在 HIV 诊断时 CD4 细胞计数的性别差异。
回顾了 2007 年 1 月至 2008 年 12 月期间在费城城市健康中心接受 HIV 护理的外国出生个体的记录。提取的数据包括人口统计学、原籍国、HIV 检测原因以及基线 CD4 细胞计数。通过性别和原籍世界区域(非洲或非非洲)评估基线 CD4 细胞计数、人口统计学变量和检测原因之间的关联。
在审查期间,107 名非洲患者和 127 名非非洲患者符合纳入标准。非洲男性的诊断时 CD4 细胞计数平均值为 263 个细胞/mm3,非洲女性为 362 个细胞/mm3(p =.055)。对于其他外国出生的个体,CD4 细胞计数平均值不因性别而异。与非洲男性相比,非洲女性更有可能在生殖保健环境中进行常规检测,而非非洲女性的生殖相关检测率则没有性别差异。
费城的非洲男性比非洲女性更晚被诊断出患有 HIV。这种差异与非洲女性在生殖保健环境中进行常规检测的比例较高有关。美国迫切需要努力让非洲男性参与常规 HIV 检测,这是 HIV 检测和联系护理的国家“检测和治疗”策略的一部分。