Choi Pahn Kyu, Chung Ji Yeon, Lee Seung Jae, Kang Hyun Goo
Department of Neurology, Chosun University School of Medicine and Hospital, Gwang-ju.
Department of Chemistry.
Medicine (Baltimore). 2018 Sep;97(39):e12480. doi: 10.1097/MD.0000000000012480.
Cerebral microbleeds are lesions that appear as round low signal intensity areas with a diameter of 2-5 mm on gradient echo T2-weighted sequence magnetic resonance imaging. Cerebral microblees are hemorrhages found in the brain parenchyma and they are caused by the extravasation of the blood. Although more patients with ischemic stroke are found to have cerebral microbleeds, only a few studies have evaluated other neurologic abnormalities outside of cognitive dysfunction due to cerebral microbleeds.
A 73-year-old female patient had only a lacunar infarction with the development of a new microbleed whenever a new neurologic symptom occurred, without the occurrence of acute ischemic stroke.
A 73-year-old female patient diagnosed symptomatic cerebral microbleeds.
Brain magnetic resonance imaging was taken within a few hours of the occurrence of a new symptom and we confirmed increased cerebral microbleeds in the ventral-posterolateral area of the thalamus, consistent with the symptoms.
This case study is meaningful because it proves that repeated occurrences of cerebral microbleeds in a specific area can induce acute ischemic stroke-like symptoms.
Cerebral microbleeds have been considered to be asymptomatic lesions thus far. However, recent studies have reported the association of cerebral microbleeds with neurological symptoms including cognitive dysfunction. This study confirmed the presence of newly formed cerebral microbleeds through imaging follow-ups whenever a symptom occurred.
脑微出血是在梯度回波T2加权序列磁共振成像上表现为直径2 - 5毫米的圆形低信号强度区域的病变。脑微出血是在脑实质中发现的出血,由血液外渗引起。虽然发现更多缺血性中风患者有脑微出血,但只有少数研究评估了脑微出血导致的认知功能障碍之外的其他神经学异常。
一名73岁女性患者仅有腔隙性梗死,每当出现新的神经症状时就会出现新的微出血,未发生急性缺血性中风。
一名73岁女性患者被诊断为有症状性脑微出血。
在出现新症状后的几小时内进行脑部磁共振成像,我们证实丘脑腹后外侧区域的脑微出血增加,与症状相符。
本病例研究具有意义,因为它证明特定区域脑微出血的反复出现可诱发急性缺血性中风样症状。
迄今为止,脑微出血一直被认为是无症状病变。然而,最近的研究报告了脑微出血与包括认知功能障碍在内的神经症状之间的关联。本研究通过症状出现时的影像学随访证实了新形成的脑微出血的存在。