将疫苗学概念扩展至新生儿多重耐药性脓毒症的控制
Extending the Concept of Vaccinology to the Control of Multidrug-resistant Sepsis in Neonates.
作者信息
Gengaimuthu Karthikeyan
机构信息
Neonatology and Pediatrics, International Modern Hospital, Dubai, ARE.
出版信息
Cureus. 2018 Jul 31;10(7):e3077. doi: 10.7759/cureus.3077.
Abstract
Standard infection control bundles have not been consistently effective in combating sepsis due to multidrug-resistant organisms (MDROs). Recent trials showing the beneficial effects of probiotics in controlling late-onset sepsis, the so-called "cross-contamination" or "cross-colonization" phenomenon that draws a parallel with the herd immunity concept in vaccinology. This editorial highlights the putative benefits of adapting the vaccinology-based concept using probiotic bacteria in our combat against MDROs.
摘要
标准感染控制集束措施在对抗由多重耐药菌（MDROs）引起的败血症方面并不总是有效。最近的试验表明益生菌在控制迟发性败血症方面具有有益效果，即所谓的“交叉污染”或“交叉定植”现象，这与疫苗学中的群体免疫概念相似。这篇社论强调了在对抗多重耐药菌的斗争中采用基于疫苗学概念的益生菌可能带来的益处。
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本文引用的文献
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Cureus. 2018 May 25;10(5):e2691. doi: 10.7759/cureus.2691.
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