新生儿重症监护病房中益生菌使用的交叉污染（交叉定植）现象：可能的机制以及临床和研究意义
The Cross Contamination (Cross Colonization) Phenomenon of Probiotic Use in Neonatal Intensive Care Units: Putative Mechanisms and Clinical and Research Implications.
作者信息
Gengaimuthu Karthikeyan
机构信息
Neonatology and Pediatrics, International Modern Hospital, Dubai, ARE.
出版信息
Cureus. 2018 May 25;10(5):e2691. doi: 10.7759/cureus.2691.
Abstract
In studies of probiotic use in neonates the phenomenon of cross contamination (cross colonization) of the control group neonates with the probiotics administered to the study group was observed and a hypothetical reanalysis of the presented data after statistically controlling this phenomenon unveils significant benefits resulting from probiotic therapy. This article discusses the putative pathogenesis of this phenomenon and its clinical and research implications.
摘要
在新生儿益生菌使用的研究中，观察到给予研究组的益生菌对对照组新生儿产生交叉污染（交叉定植）的现象，对呈现的数据在对该现象进行统计学控制后进行的假设性重新分析揭示了益生菌治疗带来的显著益处。本文讨论了这一现象的假定发病机制及其临床和研究意义。
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