Panchenkov R T, Penin V A, Kuznetsov E V
Farmakol Toksikol. 1977 May-Jun;40(3):333-6.
Induction of contrical into Wirsung's duct is shown to lessen the total proteolytic amylolytic and lipolytic action of the pancreatic juice, blood and urine, normalizing by this token the exo- and endosecretion of the pancreas. It is also shown that in acute pancreatitis there is in evidence hyperfunction of the acinar glandular cells, responsible for the synthesis of the secretion, and their focal destruction. Introduction of contrical into Wirsung's duct degrades intracellular processes of the secretion synthesis.
将抑肽酶注入胰管可减少胰液、血液和尿液中的总蛋白水解、淀粉水解和脂肪水解作用,从而使胰腺的外分泌和内分泌功能恢复正常。研究还表明,在急性胰腺炎中,负责分泌合成的腺泡腺细胞存在功能亢进以及局灶性破坏。将抑肽酶注入胰管可降低分泌合成的细胞内过程。