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一例罕见的同时性多灶性颅脊髓血管外皮细胞瘤

A Rare Case of Simultaneous Multifocal Craniospinal Hemangiopericytomas.

作者信息

Singh Harnarayan, Patir Rana, Gupta Anurag, Vaishya Sandeep

机构信息

Department of Neurosurgery, Fortis Memorial Research Institute, Gurgaon, Haryana, India.

出版信息

Asian J Neurosurg. 2018 Jul-Sep;13(3):885-887. doi: 10.4103/ajns.AJNS_356_16.

DOI:10.4103/ajns.AJNS_356_16
PMID:30283574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6159097/
Abstract

First reported case of simultaneous occurrence of hemangiopericytomas(HCP) at multiple sites of craniospinal axis in a thirty four year male is presented. Patient presented with neck pain for 1 year, and one episode of simple partial seizure involving his left lower limb. He was diagnosed as having HCP in right middle one third parasagittal region, and C4,5 vertebral bodies. Another lesion was present in L5 vertebra, which was radiologically similar to the cervical lesion, but not biopsy proven. High index of suspicion, and low threshold for screening, for coexistence of spinal HCP, in patients harboring cranial HCP's and complaints of back pain.

摘要

本文报告了首例34岁男性患者在颅脊柱轴多个部位同时发生血管外皮细胞瘤(HCP)的病例。患者出现颈部疼痛1年,并有一次累及左下肢的单纯部分性发作。他被诊断为右侧中三分之一矢状旁区域及C4、5椎体患有HCP。L5椎体存在另一个病变,影像学上与颈部病变相似,但未经活检证实。对于患有颅骨HCP且有背痛主诉的患者,应高度怀疑并降低筛查阈值,以排查脊柱HCP的共存情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b19/6159097/2dd54f537175/AJNS-13-885-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b19/6159097/2dd54f537175/AJNS-13-885-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b19/6159097/2dd54f537175/AJNS-13-885-g001.jpg

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本文引用的文献

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The evolving classification of soft tissue tumours - an update based on the new 2013 WHO classification.软组织肿瘤的不断演变的分类——基于新的 2013 年 WHO 分类的更新。
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Spinal metastasis from malignant meningeal intracranial hemangiopericytoma: one-staged percutaneous Onyx™ embolization and resection - a technical innovation.颅内硬脑膜血管外皮细胞瘤恶性脊髓转移的一期经皮 ONYX™ 栓塞和切除术:技术创新。
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Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein.脑膜血管外皮细胞瘤和孤立性纤维瘤携带 NAB2-STAT6 融合基因,可通过 STAT6 蛋白核表达进行诊断。
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Primary CNS hemangiopericytoma presenting as an intraparenchymal mass--case report and review of literature.表现为脑实质内肿块的原发性中枢神经系统血管外皮细胞瘤——病例报告及文献复习
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Meningeal hemangiopericytoma of the posterior fossa and thoracic spinal epidural space: case report.后颅窝和胸段脊髓硬膜外间隙的脑膜血管外皮细胞瘤:病例报告
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