Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.
Department of Medical Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.
Support Care Cancer. 2019 Jan;27(1):87-95. doi: 10.1007/s00520-018-4464-y. Epub 2018 Oct 3.
Chemotherapy-induced nausea and vomiting (CINV) is a common toxicity that may impair the quality of life of patients with a variety of early- and end-stage malignancies. In light of recent changes in the optimal management of CINV, we undertook this narrative review to compare the latest guidelines published by ASCO (2017), NCCN (2018), and MASCC/ESMO (2016). The processes undertaken by each organization to evaluate existing literature were also described. Although ASCO, NCCN, and MASCC/ESMO guidelines for the treatment and prevention of CINV share many fundamental similarities, literature surrounding low and minimal emetic risk regimens is lacking. Data regarding the use of complementary alternative medicine for CINV is particularly scarce and in need of further investigation.
化疗引起的恶心和呕吐（CINV）是一种常见的毒性反应，可能会降低各种早期和晚期恶性肿瘤患者的生活质量。鉴于 CINV 的最佳管理方法最近发生了变化，我们进行了这次叙述性综述，以比较 ASCO（2017 年）、NCCN（2018 年）和 MASCC/ESMO（2016 年）发布的最新指南。还描述了每个组织评估现有文献所采用的过程。尽管 ASCO、NCCN 和 MASCC/ESMO 治疗和预防 CINV 的指南有许多基本相似之处，但针对低和最小致吐风险方案的文献却很少。关于 CINV 中使用补充和替代医学的数据尤其稀缺，需要进一步研究。
