Della Rocca Foscarina, Zoleo Miranda, Pignatiello Francesca, De Lazzari Fabia, Frigo Anna Chiara, Vettore Gianna, Favretto Donata, Snenghi Rossella
Pronto Soccorso, Azienda Ospedaliera di Padova, Padua, Italy.
Scuola di Specializzazione Medicina Emergenza Urgenza, Università degli Studi di Padova, Padua, Italy.
Ann Ist Super Sanita. 2018 Jul-Sep;54(3):201-207. doi: 10.4415/ANN_18_03_06.
Driving under the influence of alcohol and/or psychoactive substances increases the risk of road accidents, but it is controversial whether this affects site and severity of injuries.
We search for alcohol, cannabinoids, cocaine, benzodiazepines, opioids, methadone, amphetamines and barbiturates in biological fluids of 1764 traumatized drivers admitted to the Emergency Department (ED) of Padua between 2010 and 2014.
We note correlation between alcohol and benzodiazepines and admission in ICU and between all the intoxications and the reserved prognosis. The sites of injuries were: head (37.13%), maxillofacial (8.33%), spinal column (44.67%), thoracic (15.31%), abdominal (5%), pelvic (2.55%) and limb traumas (23.58%). We observed a correlation between head trauma (p < 0.0001), maxillofacial trauma (p = 0.0418), thoracic trauma (p = 0.0215), pelvic trauma (p = 0.0008), spinal column trauma (p < 0.0001) and the totality of the intoxication and an association between benzodiazepines and thoracic and pelvic trauma.
Alcohol and benzodiazepines intoxication increases the risk of reserved prognosis and admission in ICU; benzodiazepines intoxication correlates with thoracic and pelvic trauma.
在酒精和/或精神活性物质影响下驾驶会增加道路交通事故风险，但这是否会影响损伤部位和严重程度仍存在争议。
我们在2010年至2014年间入住帕多瓦急诊科（ED）的1764名创伤驾驶员的生物体液中检测酒精、大麻素、可卡因、苯二氮卓类药物、阿片类药物、美沙酮、苯丙胺和巴比妥类药物。
我们注意到酒精和苯二氮卓类药物与入住重症监护病房（ICU）之间存在相关性，以及所有中毒情况与预后不良之间存在相关性。损伤部位为：头部（37.13%）、颌面（8.33%）、脊柱（44.67%）、胸部（15.31%）、腹部（5%）、骨盆（2.55%）和肢体创伤（23.58%）。我们观察到头部创伤（p < 0.0001）、颌面创伤（p = 0.0418）、胸部创伤（p = 0.0215）、骨盆创伤（p = 0.0008）、脊柱创伤（p < 0.0001）与总体中毒情况之间存在相关性，以及苯二氮卓类药物与胸部和骨盆创伤之间存在关联。
酒精和苯二氮卓类药物中毒会增加预后不良和入住ICU的风险；苯二氮卓类药物中毒与胸部和骨盆创伤相关。
