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Effect of Levetiracetam Monotherapy on Liver Enzymes and Creatine Kinase Concentrations in Children with Epilepsy: A Prospective Study.

作者信息

Attilakos Achilleas, Dinopoulos Argirios, Paschalidou Maria, Tsirouda Maria, Prasouli Alexia, Siafakas Nikos, Garoufi Anastasia

机构信息

Third Department of Pediatrics, National and Kapodistrian University of Athens, "Attikon" Hospital, Athens, Greece.

Second Department of Pediatrics, National and Kapodistrian University of Athens, "P&A Kyriakou" Children's Hospital, Athens, Greece.

出版信息

J Clin Neurol. 2018 Oct;14(4):594-595. doi: 10.3988/jcn.2018.14.4.594.

DOI:10.3988/jcn.2018.14.4.594
PMID:30284772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6172492/
Abstract
摘要

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Effect of Levetiracetam Monotherapy on Liver Enzymes and Creatine Kinase Concentrations in Children with Epilepsy: A Prospective Study.左乙拉西坦单药治疗对癫痫患儿肝酶和肌酸激酶浓度的影响：一项前瞻性研究。
J Clin Neurol. 2018 Oct;14(4):594-595. doi: 10.3988/jcn.2018.14.4.594.
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Levetiracetam Monotherapy in Children with Epilepsy: A Systematic Review.左乙拉西坦单药治疗儿童癫痫：一项系统评价。
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Levetiracetam monotherapy in children with epilepsy.左乙拉西坦单药治疗儿童癫痫
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Effect of levetiracetam monotherapy on lipid profiles and thyroid hormones in children with epilepsy: A prospective study.左乙拉西坦单药治疗对癫痫儿童血脂谱和甲状腺激素的影响：一项前瞻性研究。
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Effectiveness of Levetiracetam Monotherapy in Pediatric Patients With Epilepsy.左乙拉西坦单药治疗小儿癫痫患者的疗效
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Long-term effect of levetiracetam monotherapy on haematological parameters in children with epilepsy: A prospective study.左乙拉西坦单药治疗对癫痫患儿血液学参数的长期影响：一项前瞻性研究。
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Short-term effect of levetiracetam monotherapy on haematological parameters in children with epilepsy: a prospective study.左乙拉西坦单药治疗对癫痫患儿血液学参数的短期影响：一项前瞻性研究。
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Vitamin D deficiency in children with epilepsy taking valproate and levetiracetam as monotherapy.以丙戊酸盐和左乙拉西坦作为单一疗法的癫痫患儿的维生素D缺乏症
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The efficacy, tolerability and safety of levetiracetam therapy in a pediatric population.左乙拉西坦治疗小儿患者的疗效、耐受性及安全性。
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引用本文的文献

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Exp Ther Med. 2019 Dec;18(6):4436-4442. doi: 10.3892/etm.2019.8098. Epub 2019 Oct 14.

本文引用的文献

1
Levetiracetam Induced Increase in Creatine Phosphokinase Levels.左乙拉西坦导致肌酸磷酸激酶水平升高。
J Coll Physicians Surg Pak. 2017 Mar;27(3):S63-S64.
2
Monotherapy with Levetiracetam Versus Older AEDs: A Randomized Comparative Trial of Effects on Bone Health.左乙拉西坦单药治疗与传统抗癫痫药物的比较：对骨骼健康影响的随机对照试验
Calcif Tissue Int. 2016 Jun;98(6):556-65. doi: 10.1007/s00223-016-0109-7. Epub 2016 Feb 3.
3
Asymptomatic elevation of liver enzymes due to levetiracetam: a case report.左乙拉西坦导致的无症状性肝酶升高：一例报告
Drug Metabol Drug Interact. 2013;28(2):123-4. doi: 10.1515/dmdi-2013-0006.
4
Probable levetiracetam-related serum alkaline phosphatase elevation.可能与左乙拉西坦相关的血清碱性磷酸酶升高。
BMC Neurol. 2012 Sep 20;12:97. doi: 10.1186/1471-2377-12-97.
5
Levetiracetam: a review of its use in epilepsy.左乙拉西坦：在癫痫中的应用评价。
Drugs. 2011 Mar 5;71(4):489-514. doi: 10.2165/11204490-000000000-00000.
6
Unexpected gamma glutamyltransferase rise increase during levetiracetam monotherapy.左乙拉西坦单药治疗期间出现的γ-谷氨酰转移酶升高。
Epileptic Disord. 2010 Mar;12(1):81-2. doi: 10.1684/epd.2010.0291. Epub 2010 Feb 16.