Applegate M D, Kerr D S, Landfield P W
Brain Res. 1987 Jan 20;401(2):401-6. doi: 10.1016/0006-8993(87)91429-6.
Synaptic vesicles were quantified 20 min after the induction of long-term potentiation (LTP) in the Schaffer-commissural system of the hippocampus. With LTP, significant increases were found in vesicles attached to the active zone membrane, and in the percentage of vesicles adjacent to the active zone. In addition, as others have reported, overall vesicle density was decreased and spine area was increased. These results suggest that an increased probability of vesicle release may contribute to brain LTP.
在海马体的Schaffer-连合系统中诱导长时程增强（LTP）20分钟后，对突触小泡进行了定量分析。在LTP状态下，发现附着于活性区膜的小泡以及与活性区相邻的小泡百分比均显著增加。此外，正如其他人所报道的，总体小泡密度降低，而棘突面积增加。这些结果表明，小泡释放概率的增加可能有助于大脑的LTP。
