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首发精神病患者的污名化和歧视;首次接触精神卫生服务一年后。

Stigma and discrimination in individuals with first episode psychosis; one year after first contact with psychiatric services.

机构信息

Department of Psychological Medicine, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, 308433 Singapore.

Early Psychosis and Intervention Programme, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, 539747 Singapore.

出版信息

Psychiatry Res. 2018 Dec;270:298-305. doi: 10.1016/j.psychres.2018.09.044. Epub 2018 Sep 20.

Abstract

Stigma and discrimination in psychotic illness has not been robustly studied in those presenting with their first episode of psychosis (FEP). We prospectively examined patterns of stigma and discrimination one year after index presentation with FEP and correlates with baseline demographic, symptom burden, depression and level of functioning. We surveyed 101 subjects using the Discrimination and Stigma Scale-12 (DISC-12) and administered the Positive and Negative Syndrome Scale (PANSS), Global Assessment of Function (GAF) and the Patient Health Questionnaire (PHQ-9).  Discrimination was experienced in 76%; being shunned by people because of mental illness, making and keeping friends and from family were most affected. Older age, female gender, marital status and a family history of mental illness were significantly associated with higher unfair treatment. Higher PANSS score at baseline, 3-month and 12-month was significantly associated with lower positive treatment, higher stopping self-scores and lower overcoming stigma scores, respectively. Higher GAF score at 12-month was associated with higher overcoming stigma scores. Lower PHQ-9 scores was significantly correlated with overcoming stigma. In conclusion, stigma and discrimination is highly prevalent among individuals with FEP; the extent is associated with specific demographic variables, symptom burden, presence of depression and level of functioning. Limitations include selection bias of subjects, potential underestimation of stigma from participants who defaulted or refused to participate and inability to establish causality.

摘要

在首次出现精神病性症状(FEP)的患者中,精神疾病的污名和歧视并没有得到充分研究。我们前瞻性地研究了 FEP 首发一年后污名和歧视的模式,以及与基线人口统计学、症状负担、抑郁和功能水平的相关性。我们使用歧视和污名量表-12(DISC-12)对 101 名受试者进行了调查,并进行了阳性和阴性综合征量表(PANSS)、总体功能评估(GAF)和患者健康问卷(PHQ-9)的评估。76%的人经历过歧视;因为精神疾病而被人回避、交朋友和与家人相处最受影响。年龄较大、女性、已婚和有精神疾病家族史与更高的不公平待遇显著相关。基线、3 个月和 12 个月时的 PANSS 评分越高,与较低的积极治疗、较高的自我停止评分和较低的克服污名评分显著相关。12 个月时的 GAF 评分越高,与克服污名的评分越高显著相关。较低的 PHQ-9 评分与克服污名显著相关。总之,FEP 患者中存在高度的污名和歧视;程度与特定的人口统计学变量、症状负担、抑郁的存在和功能水平有关。局限性包括受试者的选择偏倚、失访或拒绝参与的参与者可能低估污名,以及无法确定因果关系。

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