Devlin Raymond J, Kalil David
Nurse Anesthesia Program, Louisiana State University Health Sciences Center, School of Nursing, 1900 Gravier Street, New Orleans, LA 70112, USA.
Nurse Anesthesia Program, Louisiana State University Health Sciences Center, School of Nursing, 1900 Gravier Street, New Orleans, LA 70112, USA.
Crit Care Nurs Clin North Am. 2018 Sep;30(3):e1-e9. doi: 10.1016/j.cnc.2018.05.004. Epub 2018 Jul 13.
Sepsis is a life-threatening response to infection often times requiring endotracheal intubation in critically ill patients. Etomidate is routinely used as an intravenous induction agent to provide sedation and amnesia before placing an endotracheal tube. Although etomidate has many favorable qualities, there is a major concern regarding the predictable adrenal insufficiency that follows its use. Controversy continues to this day as to whether etomidate should be avoided in the setting of sepsis or septic shock.
脓毒症是对感染的一种危及生命的反应，在重症患者中常常需要进行气管插管。依托咪酯通常用作静脉诱导剂，以便在插入气管导管前提供镇静和遗忘作用。尽管依托咪酯有许多良好特性，但使用后会出现可预测的肾上腺功能不全，这是一个主要问题。关于在脓毒症或脓毒性休克情况下是否应避免使用依托咪酯，至今仍存在争议。
