Singhal Savita Rani, Chaudhary Susheela, Agarwal Kriti, Gupta Anjali
Department of Obstetrics and Gynecology, PGIMS, Rohtak, India.
J Family Reprod Health. 2017 Dec;11(4):225-227.
To report a case of Successful Pregnancy Outcome in Recurrent Ovarian Cancer in a 26 year Old. A 26 years old primigravida presented in antenatal clinic at 23 weeks of pregnancy with recurrence of ovarian cancer of mucinous type. Following refusal of surgical management, two courses of single dose carboplatin was administered. However, before third cycle of chemotherapy could be administered ,there was deranged liver functions tests, following which elective Cesarean section with staging laparotomy was planned at 34 weeks for breech presentation with oligohydramnios. A live healthy baby girl 2.3kg was delivered. Total abdominal hysterectomy with right salpingo-oopherectomy, infracolic omentectomy, appendectomy was done. The final diagnosis was recurrent mucinous ovarian adenocarcinoma. Postoperatively, she was given six cycles of chemotherapy (carboplatin and paclitaxel). Chemotherapy and surgery, both are safe beyond first trimester and multidisciplinary treatment must be planned after taking into account the wishes of couple.
报告一例26岁复发性卵巢癌患者成功妊娠结局。一名26岁初产妇在妊娠23周时到产前门诊就诊,诊断为黏液性卵巢癌复发。在拒绝手术治疗后,给予了两疗程单剂量卡铂治疗。然而,在进行第三周期化疗之前,肝功能检查出现异常,随后因臀位伴羊水过少,计划在34周时行择期剖宫产及分期剖腹探查术。产下一名体重2.3千克的健康女婴。进行了全腹子宫切除术、右侧输卵管卵巢切除术、结肠下大网膜切除术和阑尾切除术。最终诊断为复发性黏液性卵巢腺癌。术后,她接受了六个周期的化疗(卡铂和紫杉醇)。化疗和手术在孕早期之后都是安全的,必须在考虑夫妻意愿后制定多学科治疗方案。