Schubert C, Buchholz F, Denzer-Fürst S
Geburtshilfe Frauenheilkd. 1986 Dec;46(12):902-5. doi: 10.1055/s-2008-1036342.
There are two forms of extramammary Paget's disease in respect of clinic, therapy and prognosis. In most cases (about 95%) extramammary Paget's disease is an intraepidermal manifestation of a cutaneous adenocarcinoma. After horizontal spreading within the epidermis, malignant growth continues along the adjacent adnexal structures with dermal spreading and subsequent metastases. In rare cases (approx. 5%), extramammary Paget's disease is an epidermal manifestation of an adenocarcinoma primarily located in the intestinal or urogenital tract. Further diagnostic and therapeutical procedures depend upon the type of extramammary Paget's disease.
就临床、治疗和预后而言，乳房外佩吉特病有两种形式。在大多数情况下（约95%），乳房外佩吉特病是皮肤腺癌的表皮内表现。在表皮内水平扩散后，恶性生长沿着相邻的附属结构继续向真皮扩散并随后发生转移。在罕见情况下（约5%），乳房外佩吉特病是主要位于肠道或泌尿生殖道的腺癌的表皮表现。进一步的诊断和治疗程序取决于乳房外佩吉特病的类型。
