Park Sungman, Kim Young-Jin, Kim Min Soo, Kim Hee-Sung, Kim Min-Woo, Kang Yeon-Mi, Lee Sang-Kon, Choi Kyoung-Chan, Kim Nam, Gimm Youn-Myoung, Kim Yoon-Won
Institute of Medical Science, College of Medicine, Hallym University, Chuncheon, South Korea.
Department of Microbiology, School of Medicine, Hallym University, Chuncheon, South Korea.
Bioelectromagnetics. 2018 Oct;39(7):539-546. doi: 10.1002/bem.22146. Epub 2018 Oct 5.
Accumulating evidence does not yet confirm the effect of power line frequency magnetic field (MF) on human health and fertility. We recently reported that, at continuous 60 Hz MF exposure in mice, the dose given as magnetic flux density (tesla; T) and duration of exposure was related to induce testicular germ cell apoptosis. We aimed to characterize the effect of a 20-week continuous exposure to 60 Hz MF on the motility, morphology, and number of sperm as well as the apoptosis of testicular germ cell in rats. Sprague-Dawley rats were exposed for 20 weeks to 60 Hz MF of 2, 20, or 200 μT for 24 h/day with rats exposed to sham conditions, serving as the control. The exposure to 60 Hz MF of 2 and 20 μT had no effects on testicular in this study. The exposure to 60 Hz MF of 200 μT for 20 weeks induced increases of the apoptotic cells (P < 0.001) in germ cells and decreases of sperm numbers (P < 0.05). However, the MF did not significantly affect the body or testis mass, seminiferous tubule diameter, or the motility or morphology of sperm. This study concluded that exposure to 60 Hz MF of 200 μT can increase testicular germ cell apoptosis, especially spermatogonia, and reduce sperm count. Also compared to previous mice studies, rats are less sensitive than mice to exposure to 60 Hz MF. Bioelectromagnetics. 39:539-546, 2018. © 2018 Wiley Periodicals, Inc.
越来越多的证据尚未证实 power line frequency magnetic field (MF) 对人类健康和生育能力的影响。我们最近报告称，在小鼠连续暴露于60Hz MF的情况下，以磁通密度（特斯拉；T）和暴露持续时间给出的剂量与诱导睾丸生殖细胞凋亡有关。我们旨在表征连续20周暴露于60Hz MF对大鼠精子活力、形态和数量以及睾丸生殖细胞凋亡的影响。将Sprague-Dawley大鼠每天24小时暴露于2、20或200μT的60Hz MF下20周，将暴露于假条件下的大鼠作为对照。在本研究中，暴露于2和20μT的60Hz MF对睾丸没有影响。暴露于200μT的60Hz MF 20周会导致生殖细胞中凋亡细胞增加（P < 0.001）和精子数量减少（P < 0.05）。然而，MF对体重或睾丸重量、曲细精管直径或精子活力或形态没有显著影响。本研究得出结论，暴露于200μT的60Hz MF会增加睾丸生殖细胞凋亡，尤其是精原细胞，并减少精子数量。此外，与之前的小鼠研究相比，大鼠对暴露于60Hz MF的敏感性低于小鼠。生物电磁学。39:539 - 546，2018。© 2018威利期刊公司。
