Research Unit of Gynaecology and Obstetrics, Odense University Hospital, Odense C, Denmark.
OPEN, Odense Patient data Explorative Network, Odense University Hospital, Odense C, Denmark.
BJOG. 2019 Apr;126(5):590-598. doi: 10.1111/1471-0528.15495. Epub 2018 Nov 5.
To examine the association between postpartum depression and child growth in a Tanzanian birth cohort.
Prospective cohort study.
Moshi, Tanzania.
Pregnant women over the age of 18 who sought antenatal care at two health clinics in Moshi, and the children they were pregnant with, were assessed for inclusion in this study.
The women were interviewed twice during pregnancy and three times after birth, the final follow up taking place 2-3 years postpartum. Signs of postpartum depression were assessed approximately 40 days postpartum with the Edinburgh Postnatal Depression Scale.
Child growth was assessed with anthropometric measurements at 2-3 years of age and expressed as mean z-scores.
In all, 1128 mother-child pairs were followed throughout the duration of the study. In total, 12.2% of the mothers showed signs of postpartum depression. Adjusted mean height-for-age z-score (HAZ) was significantly lower at 2-3 years follow up for children of mothers with postpartum depression than for children of mothers without (difference in HAZ: -0.32, 95% CI-0.49 to -0.15). Adjusted mean weight-for-height z-score (WHZ) was significantly increased for the children exposed to postpartum depression (difference in WHZ: 0.21, 95% CI 0.02-0.40), whereas there was no significant difference in adjusted weight-for-age z-score (WAZ; difference in WAZ: -0.04, 95% CI -0.20 to 0.12).
We found that postpartum depressive symptoms predicted decreased linear height in children at 2-3 years of age and slightly increased weight-for-height.
Postpartum depression in Tanzanian mothers is associated with impaired child growth at 2-3 years of age.
在坦桑尼亚的一个出生队列中，研究产后抑郁症与儿童生长之间的关系。
前瞻性队列研究。
坦桑尼亚莫希。
年龄在 18 岁以上的孕妇，她们在莫希的两家健康诊所寻求产前护理，以及她们怀孕的孩子。
在怀孕期间，这些女性接受了两次访谈，在分娩后接受了三次访谈，最后一次随访是在产后 2-3 年进行。在大约产后 40 天时，使用爱丁堡产后抑郁量表评估产后抑郁症的迹象。
在 2-3 岁时通过人体测量评估儿童生长情况，并以平均 z 分数表示。
在整个研究期间，共随访了 1128 对母婴。共有 12.2%的母亲出现产后抑郁症迹象。与没有产后抑郁症的母亲的孩子相比，患有产后抑郁症的母亲的孩子在 2-3 岁时的身高别年龄 z 分数（HAZ）明显较低（HAZ 差值：-0.32，95%CI-0.49 至-0.15）。暴露于产后抑郁症的儿童的体重身高 z 分数（WHZ）明显增加（WHZ 差值：0.21，95%CI 0.02 至 0.40），而体重年龄 z 分数（WAZ）没有明显差异（WAZ 差值：-0.04，95%CI-0.20 至 0.12）。
我们发现，坦桑尼亚母亲产后抑郁症状与儿童 2-3 岁时线性身高发育受损和体重身高比略有增加有关。
