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A balancing act: dual immune-checkpoint inhibition for oesophagogastric cancer.

作者信息

Harada Kazuto, Abdelhakeem Ahmed A F, Ajani Jaffer A

机构信息

Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Department of Gastroenterological Surgery, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan.

出版信息

Nat Rev Clin Oncol. 2019 Jan;16(1):9-10. doi: 10.1038/s41571-018-0108-x.

DOI:10.1038/s41571-018-0108-x
PMID:30291292
Abstract
摘要

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引用本文的文献

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An Investigator-Initiated Phase 2 Study of Nivolumab Plus Low-Dose Ipilimumab as First-Line Therapy for Microsatellite Instability-High Advanced Gastric or Esophagogastric Junction Cancer (NO LIMIT, WJOG13320G/CA209-7W7).一项研究者发起的2期研究:纳武利尤单抗联合低剂量伊匹木单抗作为微卫星高度不稳定的晚期胃癌或食管胃交界癌一线治疗方案(NO LIMIT,WJOG13320G/CA209 - 7W7)
Cancers (Basel). 2021 Feb 15;13(4):805. doi: 10.3390/cancers13040805.

本文引用的文献

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Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer.微卫星不稳定性与林奇综合征泛癌的存在相关。
J Clin Oncol. 2019 Feb 1;37(4):286-295. doi: 10.1200/JCO.18.00283. Epub 2018 Oct 30.
2
FDA Approval Summary: Pembrolizumab for Recurrent Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing PD-L1.FDA 批准概要:帕博利珠单抗用于表达 PD-L1 的复发性局部晚期或转移性胃或胃食管连接部腺癌。
Oncologist. 2019 Jan;24(1):103-109. doi: 10.1634/theoncologist.2018-0221. Epub 2018 Aug 17.