Department of Infectious Diseases, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Department of Microbiology, Laboratoire Hospitalier Universitaire de Bruxelles - Universitair Laboratorium Brussel (LHUB-ULB), Brussels, Belgium; Faculté de Médecine et Pharmacie, Université de Mons (UMONS), Mons, Belgium.
Anaerobe. 2019 Oct;59:212-214. doi: 10.1016/j.anaerobe.2018.09.010. Epub 2018 Oct 3.
Atopobium vaginae is an anaerobic Gram-positive bacterium recognized as a causative agent of bacterial vaginosis and associated with preterm delivery. Invasive infection and bacteremia have been rarely reported. We describe the case of a woman expecting her firstborn child who presented with a A. vaginae bacteremia during labor. Identification was performed using 16S rRNA gene sequencing. Both maternal and fetal outcomes were favorable due to the maternal treatment with amoxicillin-clavulanic acid. We identified three other cases in the literature with different fetal outcome. The genetic diversity of A. vaginae should be further explored in order to reveal potential strains with differential pathogenic potential.
阴道阿托波菌是一种厌氧革兰阳性菌，被认为是细菌性阴道病的病原体，并与早产有关。侵袭性感染和菌血症很少见报道。我们描述了一例初产妇在分娩时出现阴道阿托波菌菌血症的病例。鉴定是通过 16S rRNA 基因测序进行的。由于母亲接受了阿莫西林-克拉维酸治疗，母婴结局均良好。我们在文献中还发现了其他 3 例具有不同胎儿结局的病例。为了揭示潜在的具有不同致病潜力的菌株，阴道阿托波菌的遗传多样性应进一步研究。
