Kojovic Vladimir, Djordjevic Miroslav L, Vuksanovic Aleksandar
Medical School, University of Belgrade, Belgrade, Serbia.
Clinic of Urology, Clinical Center of Serbia, Belgrade, Serbia.
Int J Urol. 2019 Jan;26(1):90-95. doi: 10.1111/iju.13816. Epub 2018 Oct 7.
To present a single-stage repair of obliterative urethral strictures by simultaneous use of a buccal mucosa graft and longitudinal dorsal penile skin flap.
Between February 2007 and October 2016, 51 patients with obliterative anterior urethral stricture underwent single-stage substitution urethroplasty. A buccal mucosa graft was harvested and fixed to the corpora cavernosa as the dorsal part of the neourethra, and a vascularized dorsal penile skin flap was created, transposed ventrally and sutured to the buccal mucosa graft to form ventral part of the neourethra.
The follow-up period was 12-129 months (mean 49 months). The mean age of the patients was 48 years (range 15-71 years). The mean length of the obliterated urethral segment, measured during the operative procedure, was 5.2 cm. The etiology of strictures was: unknown, hypospadias and trauma in 19, 27 and five patients, respectively. Five patients were lost to follow up, and 46 patients were analyzed for the outcome. At the end of the follow-up period, recurrence of the stricture occurred in seven (15.2%) patients, whereas 39 (84.8%) patients did not develop stricture. An additional three (6.5%) patients developed fistula, resulting in overall successful voiding in 36 (78.3%) patients.
A combined buccal mucosa graft and longitudinal dorsal penile skin flap could be a good choice for one-stage substitution urethroplasty in complex obliterative urethral strictures, with an acceptable complication rate.
介绍一种通过同时使用颊黏膜移植物和阴茎背侧纵向皮瓣对闭塞性尿道狭窄进行一期修复的方法。
2007年2月至2016年10月,51例闭塞性前尿道狭窄患者接受了一期替代尿道成形术。获取一块颊黏膜移植物并固定于海绵体作为新尿道的背侧部分,制作带血管蒂的阴茎背侧皮瓣,将其向腹侧转移并缝合至颊黏膜移植物以形成新尿道的腹侧部分。
随访时间为12 - 129个月(平均49个月)。患者的平均年龄为48岁(范围15 - 71岁)。手术过程中测量的闭塞尿道段的平均长度为5.2 cm。狭窄的病因分别为:不明原因、尿道下裂和外伤,患者数分别为19例、27例和5例。5例患者失访,对46例患者的结果进行了分析。随访期末,7例(15.2%)患者出现狭窄复发,而39例(84.8%)患者未发生狭窄。另外3例(6.5%)患者出现瘘管,最终36例(78.3%)患者排尿成功。
对于复杂闭塞性尿道狭窄的一期替代尿道成形术,联合使用颊黏膜移植物和阴茎背侧纵向皮瓣可能是一个不错的选择,并发症发生率可接受。