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[肝硬化肝性脑病管理指南]

[Guidelines on the management of hepatic encephalopathy in cirrhosis].

出版信息

Zhonghua Nei Ke Za Zhi. 2018 Oct 1;57(10):705-718. doi: 10.3760/cma.j.issn.0578-1426.2018.10.004.

Abstract

The Chinese Society of Hepatology developed the current guidelines on the management of hepatic encephalopathy (HE) in cirrhosis based on the published evidences and panelists' consensus. The guidelines provided recommendations for the diagnosis and management of hepatic encephalopathy including minimal hepatic encephalopathy (MHE) and overt hepatic encephalopathy (OHE) emphasizing the importance on screening MHE in patients with end-stage liver diseases. The guidelines emphasized that early identification and prompt treatment are essential to improve the prognosis of HE. The principles of treatment mainly consist of eliminating precipitating factors, treating hyperammonemia to improve acute neuropsychiatric abnormalities rapidly, primary and secondary prophylaxis.

摘要

中华医学会肝病学分会基于已发表的证据和专家共识制定了当前肝硬化肝性脑病(HE)管理指南。该指南为肝性脑病(包括轻微肝性脑病[MHE]和显性肝性脑病[OHE])的诊断和管理提供了建议,强调了对终末期肝病患者筛查MHE的重要性。指南强调,早期识别和及时治疗对于改善HE的预后至关重要。治疗原则主要包括消除诱发因素、治疗高氨血症以迅速改善急性神经精神异常、一级和二级预防。

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