Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China.
Hepatology and Digestion Center, Beijing You-An Hospital, Capital Medical University, Beijing 100069, China.
World J Gastroenterol. 2019 Sep 28;25(36):5403-5422. doi: 10.3748/wjg.v25.i36.5403.
The Chinese Society of Hepatology developed the current guidelines on the management of hepatic encephalopathy in cirrhosis based on the published evidence and the panelists' consensus. The guidelines provided recommendations for the diagnosis and management of hepatic encephalopathy (HE) including minimal hepatic encephalopathy (MHE) and overt hepatic encephalopathy, emphasizing the importance on screening MHE in patients with end-stage liver diseases. The guidelines emphasized that early identification and timely treatment are the key to improve the prognosis of HE. The principles of treatment include prompt removal of the cause, recovery of acute neuropsychiatric abnormalities to baseline status, primary prevention, and secondary prevention as soon as possible.
中国肝炎学会基于已发表的证据和专家共识,制定了目前关于肝硬化性肝性脑病管理的指南。这些指南提供了肝性脑病(HE)的诊断和管理建议,包括轻微肝性脑病(MHE)和显性肝性脑病,并强调了在终末期肝病患者中筛查 MHE 的重要性。该指南强调,早期识别和及时治疗是改善 HE 预后的关键。治疗原则包括迅速去除病因、使急性神经精神异常恢复到基线状态、进行初级预防和尽快进行二级预防。