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本文引用的文献

1
Preemptive Epidural Analgesia for Postoperative Pain Relief Revisited: Comparison of Combination of Buprenorphine and Neostigmine with Combination of Buprenorphine and Ketamine in Lower Abdominal Surgeries, A Double-blind Randomized Trial.再次探讨术后疼痛缓解的预防性硬膜外镇痛:丁丙诺啡与新斯的明联合用药与丁丙诺啡与氯胺酮联合用药在下腹部手术中的比较,一项双盲随机试验
Anesth Essays Res. 2017 Oct-Dec;11(4):821-827. doi: 10.4103/aer.AER_64_17.
2
Reprint of: Efficacy and safety of different doses of dezocine for preemptive analgesia in gynecological laparoscopic surgeries: A prospective, double blind and randomized controlled clinical trial.重复出版:不同剂量地佐辛用于妇科腹腔镜手术超前镇痛的疗效和安全性:一项前瞻性、双盲、随机对照临床试验。
Int J Surg. 2018 Jan;49:84-90. doi: 10.1016/j.ijsu.2017.11.039. Epub 2017 Dec 12.
3
Analgesic effect of dezocine in different doses on elderly patients undergoing abdominal operation under general anesthesia and its influence on stress response to postoperative tracheal extubation.地佐辛不同剂量用于全麻下行腹部手术老年患者的镇痛效果及其对术后气管拔管应激反应的影响。
Eur Rev Med Pharmacol Sci. 2017 Nov;21(22):5223-5229. doi: 10.26355/eurrev_201711_13845.
4
Does inguinal hernia repair have an effect on sexual functions?腹股沟疝修补术对性功能有影响吗?
Cent European J Urol. 2016;69(2):212-6. doi: 10.5173/ceju.2016.783. Epub 2016 Jun 20.
5
Clinical study of anesthetization by dezocine combined with propofol for indolent colonoscopy.地佐辛联合丙泊酚用于无痛结肠镜检查麻醉的临床研究
World J Gastroenterol. 2016 Jun 28;22(24):5609-15. doi: 10.3748/wjg.v22.i24.5609.
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Evidence-Based Hernia Treatment in Adults.成人疝气的循证治疗
Dtsch Arztebl Int. 2016 Mar 4;113(9):150-7; quiz 158. doi: 10.3238/arztebl.2016.0150.
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Dezocine for Preventing Postoperative Pain: A Meta-Analysis of Randomized Controlled Trials.地佐辛预防术后疼痛:一项随机对照试验的荟萃分析
PLoS One. 2015 Aug 19;10(8):e0136091. doi: 10.1371/journal.pone.0136091. eCollection 2015.
8
Dexmedetomidine in Postoperative Analgesia in Patients Undergoing Hysterectomy: A CONSORT-Prospective, Randomized, Controlled Trial.右美托咪定用于子宫切除术患者术后镇痛:一项遵循CONSORT标准的前瞻性随机对照试验
Medicine (Baltimore). 2015 Aug;94(32):e1348. doi: 10.1097/MD.0000000000001348.
9
Dezocine Prevents Postoperative Hyperalgesia in Patients Undergoing Open Abdominal Surgery.地佐辛预防开腹手术患者术后痛觉过敏
Evid Based Complement Alternat Med. 2015;2015:946194. doi: 10.1155/2015/946194. Epub 2015 Jun 11.
10
Low Concentration of Dezocine in Combination With Morphine Enhance the Postoperative Analgesia for Thoracotomy.低浓度地佐辛联合吗啡增强开胸术后镇痛效果。
J Cardiothorac Vasc Anesth. 2015 Aug;29(4):950-4. doi: 10.1053/j.jvca.2014.08.012. Epub 2014 Dec 24.

术前使用地佐辛进行局部麻醉对腹股沟疝修补术患者的镇痛效果。

Analgesic effect of preoperative dezocine-based local anesthesia in patients undergoing inguinal hernia repair.

作者信息

Liu Xingwen, Hu Jing, Gao Liqun, Ji Xuewen, Zhai Duxiu, Song Huixia, Wu Xueying, Wang Liying

机构信息

Department of Liver Transplantation and Laparoscopic Surgery, Digestive and Vascular Surgery Centre, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.

出版信息

J Int Med Res. 2018 Dec;46(12):4945-4951. doi: 10.1177/0300060518781708. Epub 2018 Oct 8.

DOI:10.1177/0300060518781708
PMID:30293467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6300948/
Abstract

OBJECTIVE

This study was performed to investigate the analgesic effects of intramuscular injection of dezocine-based local anesthesia in patients undergoing inguinal hernia repair.

METHODS

A total of 120 patients underwent local herniorrhaphy from July 2015 to December 2016 and were randomly divided into 2 groups: the dezocine group, in which a preoperative intramuscular injection of dezocine was administered, and the control group, in which no dezocine injection was administered. The patients' pain and comfort levels were evaluated at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours postoperatively.

RESULTS

The visual analog scale scores at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours were significantly lower in the dezocine than control group. In the Bruggemann comfort scale evaluation, patients who received dezocine injections showed significantly greater comfort than those in the control group at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours. No adverse reactions occurred in the dezocine group.

CONCLUSIONS

Dezocine-based local anesthesia can attenuate postoperative pain and increase the comfort level during and after herniorrhaphy.

摘要

目的

本研究旨在探讨腹股沟疝修补术患者肌内注射地佐辛基础局部麻醉的镇痛效果。

方法

2015年7月至2016年12月,共有120例患者接受局部疝修补术,并随机分为两组:地佐辛组,术前肌内注射地佐辛;对照组,未注射地佐辛。在术后30分钟、2小时、6小时、12小时和24小时评估患者的疼痛和舒适度。

结果

地佐辛组术后30分钟、2小时、6小时、12小时和24小时的视觉模拟评分显著低于对照组。在布鲁格曼舒适度量表评估中,接受地佐辛注射的患者在术后30分钟、2小时、6小时、12小时和24小时的舒适度明显高于对照组。地佐辛组未发生不良反应。

结论

地佐辛基础局部麻醉可减轻疝修补术后疼痛,提高术中及术后舒适度。