Liu Xingwen, Hu Jing, Gao Liqun, Ji Xuewen, Zhai Duxiu, Song Huixia, Wu Xueying, Wang Liying
Department of Liver Transplantation and Laparoscopic Surgery, Digestive and Vascular Surgery Centre, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
J Int Med Res. 2018 Dec;46(12):4945-4951. doi: 10.1177/0300060518781708. Epub 2018 Oct 8.
This study was performed to investigate the analgesic effects of intramuscular injection of dezocine-based local anesthesia in patients undergoing inguinal hernia repair.
A total of 120 patients underwent local herniorrhaphy from July 2015 to December 2016 and were randomly divided into 2 groups: the dezocine group, in which a preoperative intramuscular injection of dezocine was administered, and the control group, in which no dezocine injection was administered. The patients' pain and comfort levels were evaluated at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours postoperatively.
The visual analog scale scores at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours were significantly lower in the dezocine than control group. In the Bruggemann comfort scale evaluation, patients who received dezocine injections showed significantly greater comfort than those in the control group at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours. No adverse reactions occurred in the dezocine group.
Dezocine-based local anesthesia can attenuate postoperative pain and increase the comfort level during and after herniorrhaphy.
本研究旨在探讨腹股沟疝修补术患者肌内注射地佐辛基础局部麻醉的镇痛效果。
2015年7月至2016年12月,共有120例患者接受局部疝修补术,并随机分为两组:地佐辛组,术前肌内注射地佐辛;对照组,未注射地佐辛。在术后30分钟、2小时、6小时、12小时和24小时评估患者的疼痛和舒适度。
地佐辛组术后30分钟、2小时、6小时、12小时和24小时的视觉模拟评分显著低于对照组。在布鲁格曼舒适度量表评估中,接受地佐辛注射的患者在术后30分钟、2小时、6小时、12小时和24小时的舒适度明显高于对照组。地佐辛组未发生不良反应。
地佐辛基础局部麻醉可减轻疝修补术后疼痛,提高术中及术后舒适度。