中性粒细胞与淋巴细胞比值在脓毒症早期和晚期的诊断及预后作用
Diagnostic and Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Early and Late Phase of Sepsis.
作者信息
Kaushik Rajnish, Gupta Monika, Sharma Madhu, Jash Debraj, Jain Neetu, Sinha Nitin, Chaudhry Aditya, Chaudhry Dhruva
机构信息
Departments of Pulmonary and Critical Care Medicine, Pt B.D. Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India.
Department of pathology, Pt B.D. Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India.
出版信息
Indian J Crit Care Med. 2018 Sep;22(9):660-663. doi: 10.4103/ijccm.IJCCM_59_18.
OBJECTIVE
Early diagnosis of sepsis is necessary to decrease morbidity and mortality. This study aims to evaluate neutrophil-to-lymphocyte ratio (NLR) as diagnostic and prognostic of early and late phase of sepsis.
METHODS
It was a prospective, observational study, conducted in Intensive Care and High Dependency Unit (Daycare) of the Department of Pulmonary and Critical Care Medicine (tertiary care center), Rohtak, from January 2017 to December 2017. A total of 56 cases of newly diagnosed cases of sepsis were included in the study and 20 healthy adults were taken as controls. Daily NLR was calculated in cases till the primary outcome.
RESULTS
The results suggested that NLR seems to have promising role as diagnostic and prognostic marker (with = 0.001 and = 0.045, respectively) in sepsis.
CONCLUSION
The study suggests that NLR can be a useful diagnostic and prognostic marker in sepsis.
目的
早期诊断脓毒症对于降低发病率和死亡率至关重要。本研究旨在评估中性粒细胞与淋巴细胞比值（NLR）在脓毒症早期和晚期的诊断及预后价值。
方法
这是一项前瞻性观察性研究，于2017年1月至2017年12月在罗塔克市肺与重症医学科（三级医疗中心）的重症监护和高依赖病房（日间护理）进行。本研究共纳入56例新诊断的脓毒症病例，并选取20名健康成年人作为对照。在病例中每日计算NLR直至得出主要结果。
结果
结果表明，NLR在脓毒症中似乎具有作为诊断和预后标志物的潜在作用（分别为P = 0.001和P = 0.045）。
结论
该研究表明，NLR在脓毒症中可能是一种有用的诊断和预后标志物。
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