Rabiei Maryam, Leili Ehsan Kazemnezhad, Alizadeh Leili
Department of Oral and Maxillofacial Medicine, Dental School, Guilan University of Medical Sciences, Rasht, Iran.
Department of Biostatistics, Faculty of Midwifery and Nursing, Guilan University of Medical Sciences, Rasht, Iran.
Contemp Clin Dent. 2018 Sep;9(Suppl 2):S256-S260. doi: 10.4103/ccd.ccd_175_18.
Burning mouth syndrome (BMS) may be defined as a burning sensation in the oral mucosa usually unaccompanied by clinical signs. Multiple conditions have been attributed to a burning sensation. The aim of this study was to determine the role of age and sex in BMS.
A total of 195 consecutive patients with BMS and 95 healthy patients without burning sensation were recruited in this study. Patients with BMS had experienced oral, burning sensations for at least 6 months without oral clinical signs, and with a normal blood count. Multiple logistic regression analyses were utilized to define the main predictors.
Menopause, candidiasis, psychological disorders, job status, denture, and dry mouth were significantly frequent in BMS patients. Multivariate logistic regression indicated age (odds ratio (OR) =1.12, 95% confidence interval (CI): 1.08-1.15, < 0.0001) and sex (OR = 3.14, 95% CI: 1.4-6.7, < 0.002) significantly increase the odds of BMS. Psychological disorders (OR = 3.39, 95% CI: 1.2-9.5, < 0.02) and candidiasis remain as predictive factors. Ultimately, age was defined as a critical predictor. Moreover, we can therefore predict that a 60-year-old woman with psychological disorders is 25 times more likely to suffer from BMS than a man 10 years younger who has no psychological disorder.
Age and sex were the main predictors in BMS. Psychological disorders and candidiasis were significantly associated with the occurrence of BMS.
灼口综合征（BMS）可定义为口腔黏膜的烧灼感，通常无临床体征。多种情况可导致烧灼感。本研究的目的是确定年龄和性别在灼口综合征中的作用。
本研究共纳入195例连续的灼口综合征患者和95例无烧灼感的健康患者。灼口综合征患者经历口腔烧灼感至少6个月，无口腔临床体征，且血常规正常。采用多元逻辑回归分析来确定主要预测因素。
绝经、念珠菌病、心理障碍、工作状态、假牙和口干在灼口综合征患者中显著更常见。多变量逻辑回归表明年龄（比值比（OR）=1.12，95%置信区间（CI）：1.08 - 1.15，P < 0.0001）和性别（OR = 3.14，95% CI：1.4 - 6.7，P < 0.002）显著增加灼口综合征的发病几率。心理障碍（OR = 3.39，95% CI：1.2 - 9.5，P < 0.02）和念珠菌病仍是预测因素。最终，年龄被确定为关键预测因素。此外，我们因此可以预测，一名患有心理障碍的60岁女性患灼口综合征的可能性是一名没有心理障碍且年龄小10岁男性的25倍。
年龄和性别是灼口综合征的主要预测因素。心理障碍和念珠菌病与灼口综合征的发生显著相关。
