Department of Oral Medicine, RSU Institute of Stomatology, Rīga Stradiņš University, LV-1007 Riga, Latvia.
Medicina (Kaunas). 2022 Aug 1;58(8):1029. doi: 10.3390/medicina58081029.
Burning mouth syndrome (BMS) is a state in which a patient experiences intraoral burning or a dysesthetic sensation without clinically evident causative lesions in the oropharyngeal area. The disorder is linked to a variety of conditions, including dry mouth, , and bacterial infections. The aim of this study was to determine the incidence of oral and/or bacterial infections among patients with BMS and whether they have an effect on pain/burning and salivary flow levels. Objectives: (1) Gather patient data regarding the presence of oral infections, dry mouth, and pain levels in the morning, afternoon, and evening periods; (2) data analysis and assessment to determine medians, means, frequencies, correlations, and statistically significant differences between patient groups. : Overall, 173 patients (23 males and 150 females) with BMS and 13 controls (five males and eight females) took part in the study. We measured pain/burning levels, unstimulated and stimulated salivary flow, the percentage of patients infected with species and/or bacterial species, and the said species growth in Petri dishes. : was the most commonly found infection among patients with BMS ( = 28, 16.2%). Overall, 21.4% patients with BMS were diagnosed with either or another species. had the richest growth among patients with BMS (7.5% out of the infected 10.4% BMS patients). No statistical significance could be noted between the existence of either species or bacterial species infections and changes in pain/burning and salivary flow levels. Negative correlations were noted between age and unstimulated and stimulated salivary flow, and positive correlations were noted between age and andspecific bacteria species' growth levels. : Although patients with present bacterial or infections showed a marginal increase in pain/burning levels, no direct statistically significant associations could be made between the presence of species or other bacteria and the symptoms among patients with BMS.
口腔烧灼感综合征（BMS）是一种患者在口咽部无明显临床病因性病变的情况下出现口腔烧灼感或感觉异常的状态。该疾病与多种情况有关，包括口干、、细菌感染等。本研究旨在确定 BMS 患者口腔和/或细菌感染的发生率，以及它们是否会影响疼痛/烧灼感和唾液流量水平。目的：（1）收集患者有关口腔感染、口干以及早晨、下午和晚上疼痛程度的数据；（2）进行数据分析和评估，以确定患者组之间的中位数、平均值、频率、相关性和统计学差异。方法：共有 173 名 BMS 患者（23 名男性和 150 名女性）和 13 名对照组（5 名男性和 8 名女性）参加了研究。我们测量了疼痛/烧灼感水平、非刺激性和刺激性唾液流量、感染 种和/或细菌种的患者比例以及在培养皿中这些种的生长情况。结果：BMS 患者中最常见的感染是（=28，16.2%）。总体而言，21.4%的 BMS 患者被诊断为感染了或另一种。在 BMS 患者中，生长最为丰富（感染的 10.4% BMS 患者中有 7.5%）。未发现存在或细菌种感染与疼痛/烧灼感和唾液流量水平变化之间存在统计学意义。年龄与非刺激性和刺激性唾液流量呈负相关，与和特定细菌种的生长水平呈正相关。结论：尽管存在细菌或感染的患者疼痛/烧灼感水平略有升高，但无法在 BMS 患者中存在种或其他细菌与症状之间建立直接的统计学关联。
