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一名肝硬化患者发生侵袭性鼻脑毛霉菌病,导致致命的大面积中风。

Invasive rhinocerebral mucormycosis in a patient with liver cirrhosis leading to fatal massive stroke.

作者信息

Sabobeh Taher, Mushtaq Kamran, Elsotouhy Ahmed, Ammar Adham A, Rashid Sameera

机构信息

Hamad Medical Corporation, Al-Sadd, Doha 3050, Qatar.

出版信息

Med Mycol Case Rep. 2018 Sep 21;22:69-73. doi: 10.1016/j.mmcr.2018.09.006. eCollection 2018 Dec.

DOI:10.1016/j.mmcr.2018.09.006
PMID:30294535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6169250/
Abstract

Immunocompromised status is associated with invasive fungal infections including mucormycosis. These infections are challenging to treat and associated with high overall mortality. Here we report a fatal case of invasive mucormycosis in a cirrhotic, diabetic patient. Despite the swift diagnosis and management; the fungal invasion of the right internal carotid artery lead to massive ischemic stroke. Timely diagnosis and management is crucial for management but it seems not always enough and new approaches for treatment must be sought.

摘要

免疫功能低下状态与包括毛霉菌病在内的侵袭性真菌感染有关。这些感染治疗具有挑战性,且总体死亡率很高。在此,我们报告一例肝硬化糖尿病患者发生的致命性侵袭性毛霉菌病病例。尽管诊断和治疗迅速,但右侧颈内动脉的真菌侵袭导致了大面积缺血性中风。及时诊断和治疗对于管理至关重要,但似乎并不总是足够的,必须寻求新的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/bb8abe468bd5/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/ed2c0d2a1a24/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/f1a1133f3e7a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/9a97aa19d1d1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/6802a6528f49/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/38e244604c8c/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/bb8abe468bd5/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/ed2c0d2a1a24/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/f1a1133f3e7a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/9a97aa19d1d1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/6802a6528f49/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/38e244604c8c/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa2/6169250/bb8abe468bd5/gr6.jpg

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A tip from the nose: rhinocerebral mucormycosis in a patient with alcoholic liver cirrhosis and cocaine abuse, an uncommon association.来自鼻子的提示:一名酒精性肝硬化和滥用可卡因患者的鼻脑毛霉菌病,一种不常见的关联。
BMJ Case Rep. 2017 Aug 7;2017:bcr-2017-220730. doi: 10.1136/bcr-2017-220730.
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Initial use of combination treatment does not impact survival of 106 patients with haematologic malignancies and mucormycosis: a propensity score analysis.
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Diabetes Metab Syndr. 2021 Sep-Oct;15(5):102267. doi: 10.1016/j.dsx.2021.102267. Epub 2021 Sep 1.
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