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通过住院医师培训实施ADA/AACE指南对住院高血糖患者管理的影响:一项三级医疗中心研究

Effect of Implementation of ADA/AACE Guidelines on the Management of Hospitalized Hyperglycemic Patients Through Training of Residents: A Tertiary Care Center Study.

作者信息

Amrith B P, Sethi Prayas, Soneja Manish, Vikram Naval, Kumar Arvind, Aggarwal Praveen, Jyotsna Viveka P, Pandey R M, Wig Naveet

机构信息

Department of Medicine, All India Institute of Medical Science, New Delhi, India.

Department of Emergency Medicine, All India Institute of Medical Science, New Delhi, India.

出版信息

Indian J Endocrinol Metab. 2018 Sep-Oct;22(5):616-620. doi: 10.4103/ijem.IJEM_698_17.

DOI:10.4103/ijem.IJEM_698_17
PMID:30294569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6166556/
Abstract

BACKGROUND

Hyperglycemia is a common comorbidity in hospitalized patients and may add to adverse outcomes. Various associations have issued guidelines for optimal management of hyperglycemia in ill patients. This study aims to assess the adherence to current guidelines in inpatient setting and the impact of educational interventions on the improvement in adherence to guidelines as well as its effect on the level of blood sugar control and patient outcomes.

MATERIALS AND METHODS

It was a quasi-experimental pretest and posttest study and was done in three phases, viz., observation of current practices, intervention in the form of educational interventions, and its effect on change in practices and patient outcomes.

RESULTS

There was statistically significant 22% increase in the use of recommended insulin regimens ( = 0.028). The proportion of blood sugars within recommended range in the first 48 h, mean daily blood sugars, and the incidence of severe hyperglycemia improved in phase 3 vs phase 1 and was statistically significant. On comparing the subgroups, viz., those who followed and those who did not follow the guidelines, the results of the proportion of blood sugar in recommended range and proportions of blood sugar of more than 250 were found to be statistically significant.

CONCLUSION

Dedicated educational interventions help in improving healthcare practices. According to current guidelines, rapid improvement in hyperglycemia and better glycemic control occur with adherence to protocol-based management of hyperglycemia.

摘要

背景

高血糖是住院患者常见的合并症,可能会增加不良后果。多个协会已发布了针对患病患者高血糖最佳管理的指南。本研究旨在评估住院环境中对现行指南的遵循情况,以及教育干预对提高指南遵循率的影响,及其对血糖控制水平和患者预后的作用。

材料与方法

这是一项准实验性的前测和后测研究,分三个阶段进行,即观察当前做法、以教育干预形式进行干预,以及其对做法改变和患者预后的影响。

结果

推荐胰岛素方案的使用有统计学意义地增加了22%(P = 0.028)。与第1阶段相比,第3阶段在最初48小时内血糖处于推荐范围内的比例、平均每日血糖以及严重高血糖的发生率均有所改善,且具有统计学意义。在比较遵循和未遵循指南的亚组时,发现血糖在推荐范围内的比例以及血糖高于250的比例结果具有统计学意义。

结论

专门的教育干预有助于改善医疗实践。根据现行指南,通过遵循基于方案的高血糖管理,高血糖可迅速改善,血糖控制更佳。

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本文引用的文献

1
Can a single interactive seminar durably improve knowledge and confidence of hospital diabetes management?单次互动研讨会能否持久提高医院糖尿病管理的知识和信心?
Clin Diabetes Endocrinol. 2016 Dec 1;2:20. doi: 10.1186/s40842-016-0038-4. eCollection 2016.
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Consensus evidence-based guidelines for in-patient management of hyperglycaemia in non-critical care setting as per Indian clinical practice.根据印度临床实践制定的非重症监护环境下高血糖住院管理的基于证据的共识指南。
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Audit and feedback: effects on professional practice and healthcare outcomes.审核与反馈:对专业实践和医疗结果的影响。
Cochrane Database Syst Rev. 2012 Jun 13;2012(6):CD000259. doi: 10.1002/14651858.CD000259.pub3.
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Effect of an educational Inpatient Diabetes Management Program on medical resident knowledge and measures of glycemic control: a randomized controlled trial.住院医师糖尿病管理教育项目对住院医师知识和血糖控制措施的影响:一项随机对照试验。
Endocr Pract. 2012 Mar-Apr;18(2):238-49. doi: 10.4158/EP11277.OR.
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Intensive insulin protocol implementation and outcomes in the medical and surgical wards at a Veterans Affairs Medical Center.在退伍军人事务医疗中心的内科和外科病房实施强化胰岛素方案的结果。
Ann Pharmacother. 2010 Feb;44(2):249-56. doi: 10.1345/aph.1M501. Epub 2010 Jan 26.
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Impact of improvement efforts on glycemic control and hypoglycemia at a university medical center.改善措施对大学医学中心血糖控制和低血糖的影响。
J Hosp Med. 2009 Jul;4(6):331-9. doi: 10.1002/jhm.449.
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Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis.危重症患者中与高血糖相关的死亡率因入院诊断而异。
Crit Care Med. 2009 Dec;37(12):3001-9. doi: 10.1097/CCM.0b013e3181b083f7.
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American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control.美国临床内分泌医师协会与美国糖尿病协会关于住院患者血糖控制的共识声明。
Endocr Pract. 2009 May-Jun;15(4):353-69. doi: 10.4158/EP09102.RA.
9
Continuing education meetings and workshops: effects on professional practice and health care outcomes.继续教育会议与研讨会:对专业实践和医疗保健结果的影响
Cochrane Database Syst Rev. 2009 Apr 15;2009(2):CD003030. doi: 10.1002/14651858.CD003030.pub2.
10
Improved inpatient use of basal insulin, reduced hypoglycemia, and improved glycemic control: effect of structured subcutaneous insulin orders and an insulin management algorithm.改善住院患者基础胰岛素的使用、减少低血糖并改善血糖控制:结构化皮下胰岛素医嘱和胰岛素管理算法的效果
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