ParaStamp and Its Applications to Cell Patterning, Drug Synergy Screening, and Rewritable Devices for Droplet Storage.

Engineered materials have been employed as versatile tools to explore the fundamental cell biology/drug development as well as to approach the intelligent device, thereby becoming the key components in modern technology. Herein, a ParaStamp technique has been revealed to possess applications for cell patterning, drug screening, and rewritable functional patterning. The ParaStamp includes a micropatterned PDMS master and a liquid-phased paraffin oil generated at high temperature, which can transfer the patterned paramembrane onto varied material surfaces, such as glass, polystyrene, and flexible foil. This technique is simple and cost-effective to meet the high-throughput requirement for industries. Taken together, our findings herein should have general insights in cell biology, biodetection, and development of smart hydrophobic surface.