The Mallat Family Laboratory of Organic Chemistry, Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Technion City, 3200009, Haifa, Israel.
Chemistry. 2019 Jan 2;25(1):205-209. doi: 10.1002/chem.201805006. Epub 2018 Nov 26.
From a single α-silylated carbinol intermediate, easily accessible by carbometallation of cyclopropenes, various scaffolds featuring a quaternary carbon stereocenter could be obtained selectively. The selectivity towards these different products was achieved by either changing the experimental conditions or the nature of the organometallic species involved.
从易于通过环丙烯的碳金属化作用获得的单 α-硅烷化 carbinol 中间体中，可以选择性地获得具有季碳立体中心的各种骨架。通过改变实验条件或所涉及的有机金属物种的性质，可以实现对这些不同产物的选择性。
