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利多卡因联合肾上腺素的扁桃体周浸润与扁桃体切除术后继发性出血风险增加有关。

Peritonsillar infiltration of lidocaine with adrenaline is associated with increased risk of secondary post-tonsillectomy haemorrhage.

作者信息

Tolska H K, Takala A J, Jero J

机构信息

Division of Anesthesiology, Department of Anesthesiology,Intensive Care and Pain Medicine,University of Helsinki and Helsinki University Hospital,Finland.

Department of Otorhinolaryngology - Head and Neck Surgery,Turku University Hospital,Finland.

出版信息

J Laryngol Otol. 2018 Oct;132(10):911-922. doi: 10.1017/S0022215118001731. Epub 2018 Oct 9.

Abstract

OBJECTIVES

In order to evaluate the safety of tonsillectomy among children, we retrospectively studied the incidence of post-operative complications, adverse events and their association with peri-operative medication.

METHODS

Data were collected from the medical records of 691 patients aged 1-16 years, including details of post-operative complications (any unplanned contact with the hospital), analgesics, dexamethasone, 5-HT3 antagonists, local anaesthetic and haemostatic agents.

RESULTS

Recovery was complicated in 13.6 per cent of patients, of whom 8.4 per cent were re-admitted to the ward. The most common complication was post-tonsillectomy haemorrhage, experienced by 7.1 per cent of patients. Re-operation under general anaesthesia (for grade III post-tonsillectomy haemorrhage) was required by 4.2 per cent of patients. Peritonsillar infiltration of lidocaine with adrenaline increased the risk of post-tonsillectomy haemorrhage (odds ratio = 4.1; 95 per cent confidence interval = 2.1 to 8.3).

CONCLUSION

Every seventh paediatric patient experienced a complicated recovery after tonsillectomy, caused by post-tonsillectomy haemorrhage in most cases. Local peritonsillar infiltration of lidocaine with adrenaline was associated with an increased risk of post-tonsillectomy haemorrhage.

摘要

目的

为评估儿童扁桃体切除术的安全性,我们回顾性研究了术后并发症、不良事件的发生率及其与围手术期用药的关系。

方法

收集了691例1至16岁患者的病历数据,包括术后并发症(任何与医院的非计划性接触)、镇痛药、地塞米松、5-羟色胺3拮抗剂、局部麻醉药和止血剂的详细信息。

结果

13.6%的患者恢复过程出现并发症,其中8.4%再次入院。最常见的并发症是扁桃体切除术后出血,7.1%的患者出现该情况。4.2%的患者需要全身麻醉下再次手术(用于Ⅲ级扁桃体切除术后出血)。利多卡因加肾上腺素扁桃体周围浸润增加了扁桃体切除术后出血的风险(比值比=4.1;95%置信区间=2.1至8.3)。

结论

每七名儿科患者中就有一名在扁桃体切除术后恢复过程出现并发症,大多数情况下是由扁桃体切除术后出血引起的。利多卡因加肾上腺素扁桃体周围局部浸润与扁桃体切除术后出血风险增加有关。

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