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中心性肥胖、性成熟加速与女童 PCOS

Central Obesity, Faster Maturation, and 'PCOS' in Girls.

机构信息

Pediatric Endocrinology, University of Leuven, Leuven, Belgium.

Pediatric Endocrinology, Hospital Josep Trueta & IDIBGI, Girona, Spain.

出版信息

Trends Endocrinol Metab. 2018 Dec;29(12):815-818. doi: 10.1016/j.tem.2018.09.005. Epub 2018 Oct 5.

DOI:10.1016/j.tem.2018.09.005
PMID:30297320
Abstract

Polycystic ovary syndrome (PCOS) development commonly starts with a mismatch between pre- and postnatal weight gain, leading to hepatovisceral fat excess. To escape from such central obesity, girls may accelerate their growth and/or maturation. This homeostatic mechanism is lost upon reaching adult height, and PCOS may ensue. Prevention and/or treatment of PCOS should aim at reducing central fat excess.

摘要

多囊卵巢综合征（PCOS）的发展通常始于产前和产后体重增加之间的不匹配，导致肝内脏脂肪过多。为了摆脱这种中心性肥胖，女孩可能会加速生长和/或成熟。一旦达到成年身高，这种体内平衡机制就会丧失，PCOS 可能随之而来。PCOS 的预防和/或治疗应旨在减少中心性肥胖。

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