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[基于病因接受治疗的慢性或复发性角膜结膜炎患者中1型和2型疱疹抗原的免疫荧光检测]

[Detection of type 1 and 2 herpetic antigens by immunofluorescence in patients with chronic or recurrent keratoconjunctivitis receiving therapy based on etiology].

作者信息

Athanasiu P, Anghelescu S, Deltin L, Pop D Popa D, Dumitrescu A M, Macarie I, Mihail V

出版信息

Virologie. 1986 Oct-Dec;37(4):247-52.

PMID:3029947
Abstract

Immunofluorescence (IF) techniques were used to evaluate the therapeutical efficiency of moroxidine hydrochloride against herpes virus (HSV) induced keratoconjunctivitis. In 56 out of the 77 followed-up and treated patients, the IF reactions revealed the presence of both types 1 and 2 of herpes virus, while in 21 only type 1 was found. The treatment with moroxidine hydrochloride led to a reduction of 63% and 92%, respectively, of the incidence of herpes virus type 1 and 2 antigens in the conjunctival cells, coincident with the improvement of clinical symptoms or persistent recovery.

摘要

采用免疫荧光(IF)技术评估盐酸吗啉胍对疱疹病毒(HSV)引起的角膜结膜炎的治疗效果。在77例接受随访和治疗的患者中,56例的IF反应显示同时存在1型和2型疱疹病毒,而21例仅发现1型。盐酸吗啉胍治疗使结膜细胞中1型和2型疱疹病毒抗原的发生率分别降低了63%和92%,同时临床症状得到改善或持续恢复。

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