Navarro Xavier, Geuna Stefano, Grothe Claudia, Haastert-Talini Kirsten
Department of Cell Biology, Physiology and Immunology, Institut de Neurociències, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Department of Clinical and Biological Sciences, University of Torino, Cavalieri Ottolenghi Institute of Neuroscience, Torino, Orbassano, Italy.
Anat Rec (Hoboken). 2018 Oct;301(10):1614-1617. doi: 10.1002/ar.23941. Epub 2018 Oct 17.
Injuries to the peripheral nerves result in loss of motor, sensory and autonomic functions in the denervated segments of the body, thus having strong impact in the quality of life of affected patients. Neurons are able to regenerate their injured axons in the peripheral nerves; however, the endogenous repair mechanisms usually do not allow for a satisfactory functional recovery, especially after severe nerve injuries. The interest on regeneration after peripheral nerve injuries has increased in the recent years due to the numerous advances derived from studies of neurobiology, cell therapy, and tissue engineering. This Thematic Papers Issue brings together a number of papers, authored by researchers in the field, which cover a wide spectrum of topics related to regeneration and repair of peripheral nerve injuries. The Issue proposal originated from the recent 4th International Symposium on Peripheral Nerve Regeneration (ISPNR2017) which was hosted by Xavier Navarro and the European Society for the Study of Peripheral Nerve Repair and Regeneration in Barcelona, Spain. Anat Rec, 301:1614-1617, 2018. © 2018 Wiley Periodicals, Inc.
周围神经损伤会导致身体失神经支配节段的运动、感觉和自主神经功能丧失,从而对受影响患者的生活质量产生重大影响。神经元能够在周围神经中再生其受损的轴突;然而,内源性修复机制通常无法实现令人满意的功能恢复,尤其是在严重神经损伤后。近年来,由于神经生物学、细胞治疗和组织工程研究取得的众多进展,对周围神经损伤后再生的关注有所增加。本期专题论文汇集了该领域研究人员撰写的多篇论文,涵盖了与周围神经损伤再生和修复相关的广泛主题。该专题的提议源于最近由哈维尔·纳瓦罗(Xavier Navarro)和欧洲周围神经修复与再生研究学会在西班牙巴塞罗那主办的第四届国际周围神经再生研讨会(ISPNR2017)。《解剖学记录》,301:1614 - 1617,2018年。© 2018威利期刊公司。