Department of Plastic and Reconstructive Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Physiology (Bethesda). 2022 Nov 1;37(6):0. doi: 10.1152/physiol.00008.2022. Epub 2022 Jul 12.
Peripheral nerve injuries often result in life-altering functional deficits even with optimal management. Unlike the central nervous system, peripheral nerves have the ability to regenerate lost axons after injury; however, axonal regeneration does not equate to full restoration of function. To overcome this physiological shortcoming, advances in nerve regeneration and repair are paramount, including electrical stimulation, gene therapy, and surgical technique advancements.
周围神经损伤即使经过最佳治疗，也常导致改变生活的功能缺陷。与中枢神经系统不同，周围神经在损伤后有能力再生丢失的轴突；然而，轴突再生并不等同于功能的完全恢复。为了克服这一生理缺陷，神经再生和修复方面的进展至关重要，包括电刺激、基因治疗和手术技术的进步。
