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股骨前弯度:1232 根成人股骨的 3D CT 分析。

Femoral antecurvation-A 3D CT Analysis of 1232 adult femurs.

机构信息

Department of Trauma, Hand, and Reconstructive Surgery, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

Stryker Trauma GmbH, Kiel-Schönkirchen, Germany.

出版信息

PLoS One. 2018 Oct 9;13(10):e0204961. doi: 10.1371/journal.pone.0204961. eCollection 2018.

Abstract

INTRODUCTION

For optimal treatment of femoral fractures, it is essential to understand the anatomical antecurvation of the human femur. Recent clinical studies have highlighted the problem of distal anterior encroachment or even perforation of the nail tip. The aim of this study was to accurately describe the femoral antecurvation in a large cohort. Another objective was to identify the most important influences on femoral antecurvation, such as age, femur length, gender and ethnicity.

METHODS

A three dimensional modelling and analytical technology was applied for the analysis of 1,232 femurs. Individual femoral antecurvation was precisely computed to determine whether gender, femur length, age, ethnicity or body mass index influence the radius of curvature (ROC).

RESULTS

The calculated mean ROC for all femurs was 943 mm. The lowest ROC of 826 mm was found in female Asian femurs. A regression analysis demonstrated that age and femur length could predict the variability of the curvature, with femoral length as most powerful predictor. A matched pair subgroup analysis between Asians and Caucasians could not show any significant differences of ROC values.

CONCLUSIONS

The mean radius of the femoral antecurvation may be smaller than previously reported revealing a significant mismatch between the actual individual anatomy and existing implants. In opposite to existing literature, this study suggests, that antecurvation differences between various ethnicities may exclusively be attributed to differences in femoral length and age. The findings of this study may be found helpful in the development of novel designs for intra- and extramedullary implants.

摘要

简介

为了实现股骨骨折的最佳治疗,了解人类股骨的解剖前弯度至关重要。最近的临床研究强调了钉尖远端前侵甚至穿透的问题。本研究的目的是在大样本中准确描述股骨前弯度。另一个目的是确定对股骨前弯度有重要影响的因素,如年龄、股骨长度、性别和种族。

方法

应用三维建模和分析技术对 1232 根股骨进行分析。精确计算个体股骨前弯度,以确定性别、股骨长度、年龄、种族或体重指数是否影响曲率半径(ROC)。

结果

所有股骨的计算平均 ROC 为 943mm。女性亚洲股骨的 ROC 最低,为 826mm。回归分析表明,年龄和股骨长度可以预测曲率的可变性,股骨长度是最有力的预测因素。亚洲人和高加索人之间的匹配对亚组分析未能显示 ROC 值有任何显著差异。

结论

股骨前弯度的平均半径可能小于先前报道的,这表明实际的个体解剖结构与现有植入物之间存在显著的不匹配。与现有文献相反,本研究表明,不同种族之间的前弯度差异可能仅归因于股骨长度和年龄的差异。本研究的发现可能有助于开发新型髓内和髓外植入物的设计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d28/6177158/e72578a4e0c9/pone.0204961.g001.jpg

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