Ramezani Mazaher, Sadeghi Masoud
Molecular Pathology Research Centre, Emam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Medical Biology Research Centre, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Prz Gastroenterol. 2018;13(3):196-199. doi: 10.5114/pg.2018.78285. Epub 2018 Sep 17.
Knowledge about oesophageal carcinoids is based primarily on case reports, and therefore information about them is incomplete.
To collect information on oesophageal carcinoid tumours in a systematic review study.
Databases including PubMed, Scopus, and Web of Science were searched for the characteristics of oesophageal carcinoid tumour. Studies included original articles, case series, or case reports, reporting at least one of the characteristics of benign carcinoid tumour or carcinoid tumour.
Out of 670 studies searched, after evaluation and excluding non-relevant studies, 14 studies were included and analysed in the systematic review. These studies included 19 patients with carcinoid tumour of whom 57.9% were males with a mean age of 55.5 years. Dysphagia and weight loss were the most prevalent symptoms and signs in the patients. Lower oesophagus was the most prevalent site of tumour.
This meta-analysis showed that the mean age at diagnosis of oesophageal carcinoid was around 55 years, with 1.4 times greater prevalence among males, and located mainly in the distal oesophagus. The mean tumour size was 2.4 cm. The main symptoms and signs of this disease were dysphagia, weight loss, and reflux. The tumour behaviour was mainly non-aggressive except for cases associated with adenocarcinoma.
关于食管类癌的知识主要基于病例报告，因此相关信息并不完整。
在一项系统评价研究中收集食管类癌肿瘤的信息。
检索包括PubMed、Scopus和Web of Science在内的数据库，以获取食管类癌肿瘤的特征。纳入的研究包括原始文章、病例系列或病例报告，报告了良性类癌肿瘤或类癌肿瘤的至少一项特征。
在检索的670项研究中，经过评估并排除不相关研究后，14项研究被纳入系统评价并进行分析。这些研究包括19例类癌肿瘤患者，其中57.9%为男性，平均年龄55.5岁。吞咽困难和体重减轻是患者中最常见的症状和体征。食管下段是最常见的肿瘤部位。
这项荟萃分析表明，食管类癌的诊断平均年龄约为55岁，男性患病率高1.4倍，主要位于食管远端。肿瘤平均大小为2.4厘米。该疾病的主要症状和体征为吞咽困难、体重减轻和反流。除与腺癌相关的病例外，肿瘤行为主要为非侵袭性。
