Haustein U F
Z Gesamte Inn Med. 1977 May 15;32(10):218-21.
Report on 3 patients with lupus-erythematosus-like syndromes, in which antinuclear antibodies in high titres and peripheral (or homogeneous) pattern--the characteristic leading immunologic phenomenon of SLE--could not be observed. The second patient suffered from the so-called pseudo-LE-syndrome described by Maas and Schubothe and characterized by antimitochondrial antibodies in high titres. The disease of the 3rd patient was explained as drug-induced LE-syndrome by Ovosiston. The variety of the antigens and antibodies directed against them, the improved diagnostics as well as the increased consumption of drugs were taken as reasons for the growing frequency of such LE-like syndromes. The coexistences, overlappings and transitional forms among the special autoimmune diseases render the diagnostics more difficult and explain the great variety of pictures of the SLE.
关于3例红斑狼疮样综合征患者的报告，在这些病例中未观察到高滴度的抗核抗体和周边型（或均质型）——系统性红斑狼疮的典型主要免疫现象。第二例患者患有Maas和Schubothe所描述的所谓假性红斑狼疮综合征，其特征为高滴度的抗线粒体抗体。第三例患者的疾病被Ovosiston解释为药物性红斑狼疮综合征。针对各种抗原及相应抗体、诊断方法的改进以及药物使用量的增加被视为这类红斑狼疮样综合征发病率上升的原因。特殊自身免疫性疾病之间的共存、重叠和过渡形式使诊断更加困难，并解释了系统性红斑狼疮临床表现的多样性。
