由活化白细胞介导的铜从铜（I）-硫蛋白转运至脱辅基血浆铜蓝蛋白的过程。
Copper transport from Cu(I)-thionein into apo-caeruloplasmin mediated by activated leucocytes.
作者信息
Schechinger T, Hartmann H J, Weser U
出版信息
Biochem J. 1986 Nov 15;240(1):281-3. doi: 10.1042/bj2400281.
Abstract
A study on the transfer of copper from Cu-thionein into apo-caeruloplasmin, using Cu-thionein that was previously oxidised by activated leucocytes, was performed. Cu(I)-thiolate oxidation was conveniently monitored by the progressive decline of the specific Cotton bands between 400 and 300 nm. The characteristic e.p.r. properties and NN-dimethyl-p-phenylenediamine oxidase activity indicated a successful formation of caeruloplasmin. Taking into account the simultaneous occurrence of leucocytes, apo-caeruloplasmin and Cu-thionein in blood plasma, such an interaction would favour a possible metabolic link between either copper protein.
摘要
利用先前被活化白细胞氧化的铜硫蛋白，开展了一项关于铜从铜硫蛋白向脱辅基血浆铜蓝蛋白转移的研究。通过400至300纳米之间特定科顿带的逐渐下降，可方便地监测硫醇铜（I）的氧化。特征性的电子顺磁共振特性和N，N-二甲基对苯二胺氧化酶活性表明成功形成了血浆铜蓝蛋白。考虑到白细胞、脱辅基血浆铜蓝蛋白和铜硫蛋白同时存在于血浆中，这种相互作用将有利于这两种铜蛋白之间可能存在的代谢联系。
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本文引用的文献
1
The purification of human caeruloplasmin.
Biochem J. 1960 Feb;74(2):279-87. doi: 10.1042/bj0740279.
2
Preparation of an apoprotein from ceruloplasmin by reversible dissociation of copper.
Science. 1958 Mar 14;127(3298):588-90. doi: 10.1126/science.127.3298.588-a.
3
Tetrahedral copper-sulphur coordination in yeast Cu-thionein. An EXAFS study.
FEBS Lett. 1982 Apr 5;140(1):19-21. doi: 10.1016/0014-5793(82)80511-5.
4
Metallothionein-I in the plasma and liver of neonatal rats.
Biochem J. 1984 Feb 1;217(3):859-62. doi: 10.1042/bj2170859.
5
Development of a radioimmunoassay for rat liver metallothionein-I and its application to the analysis of rat plasma and kidneys.
Biochem J. 1983 Aug 1;213(2):459-65. doi: 10.1042/bj2130459.
6
Oxidation of Cu(I)-thionein by enzymically generated H2O2.
Hoppe Seylers Z Physiol Chem. 1984 Nov;365(11):1355-9. doi: 10.1515/bchm2.1984.365.2.1355.
7
Yeast copper-thionein can reconstitute the Japanese-lacquer-tree (Rhus vernicifera) laccase from the Type 2-copper-depleted enzyme via a direct copper(I)-transfer mechanism.
Biochem J. 1983 May 1;211(2):515-7. doi: 10.1042/bj2110515.
8
Reconstitution of stellacyanin as a case of direct Cu(I) transfer between yeast copper thionein and 'blue' copper apoprotein.
FEBS Lett. 1983 Feb 7;152(1):94-6. doi: 10.1016/0014-5793(83)80489-x.
9
Copper(I) transfer into apo-stellacyanin using copper(I)-thiourea as a copper-thionein model.
Biochem J. 1984 Aug 1;221(3):923-5. doi: 10.1042/bj2210923.
10
Identification of an apoceruloplasmin-like substance in the plasma of copper-deficient rats.
J Biol Chem. 1970 May 10;245(9):2350-3.
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