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新生大鼠血浆和肝脏中的金属硫蛋白-I

Metallothionein-I in the plasma and liver of neonatal rats.

作者信息

Mehra R K, Bremner I

出版信息

Biochem J. 1984 Feb 1;217(3):859-62. doi: 10.1042/bj2170859.

Abstract

The concentrations of metallothionein-I in the plasma and liver of neonatal rats were measured by radioimmunoassay. Plasma concentrations of the protein in male and female 4-day-old rats were 350 and 740 ng/ml respectively, and declined rapidly to only 3.5 ng/ml at 32 days of age. Concentrations in liver were also high in the newborn rats (200 micrograms/g), and declined from 12 days of age onwards.

摘要

采用放射免疫分析法测定新生大鼠血浆和肝脏中金属硫蛋白-I的浓度。4日龄雄性和雌性大鼠血浆中该蛋白的浓度分别为350 ng/ml和740 ng/ml,并在32日龄时迅速降至仅3.5 ng/ml。新生大鼠肝脏中的浓度也很高(200微克/克),从12日龄起开始下降。

相似文献

本文引用的文献

1
A radioimmunoassay for human metallothionein.一种针对人金属硫蛋白的放射免疫测定法。
Toxicol Appl Pharmacol. 1980 Aug;55(1):94-102. doi: 10.1016/0041-008x(80)90224-0.
4
Metallothionein in plasma and urine of cadmium workers.
Environ Res. 1982 Jun;28(1):179-82. doi: 10.1016/0013-9351(82)90167-0.
9
Turnover of metallothioneins in rat liver.大鼠肝脏中金属硫蛋白的周转
Biochem J. 1978 Jul 15;174(1):327-38. doi: 10.1042/bj1740327.

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