Mehra R K, Bremner I
Biochem J. 1984 Feb 1;217(3):859-62. doi: 10.1042/bj2170859.
The concentrations of metallothionein-I in the plasma and liver of neonatal rats were measured by radioimmunoassay. Plasma concentrations of the protein in male and female 4-day-old rats were 350 and 740 ng/ml respectively, and declined rapidly to only 3.5 ng/ml at 32 days of age. Concentrations in liver were also high in the newborn rats (200 micrograms/g), and declined from 12 days of age onwards.
采用放射免疫分析法测定新生大鼠血浆和肝脏中金属硫蛋白-I的浓度。4日龄雄性和雌性大鼠血浆中该蛋白的浓度分别为350 ng/ml和740 ng/ml,并在32日龄时迅速降至仅3.5 ng/ml。新生大鼠肝脏中的浓度也很高(200微克/克),从12日龄起开始下降。