Department of Health Research Methods, Evidence and Impact, McMaster University, 237 Barton Street East, Hamilton, ON, Canada.
Department of Medicine, McMaster University, Hamilton, ON, Canada.
Europace. 2019 Mar 1;21(3):445-450. doi: 10.1093/europace/euy212.
Despite recommendations stating that surgical atrial fibrillation (AF) ablation is reasonable for patients with AF undergoing cardiac surgery for other indications, the clinical impact of this procedure remains unclear. We aimed to describe surgeons' practices and perceptions of this procedure.
We built a self-administered survey in collaboration with content and methodology experts. We surveyed 268 cardiac surgeons from 80 centres in 18 countries. The response rate was 76% (n = 204/276), 49% from North America, 39% Europe, and 12% other regions. Respondents performed a median 10 [interquartile range (IQR) 4-30] AF ablation procedures/year, with marked variation in proportions of patients with AF considered for ablation (median 25%, IQR 10-61). 94% and 80% of surgeons respectively, thought symptomatic and asymptomatic patients benefit from ablation. Surgeons estimated the added major complication rate of concomitant AF ablation at 16% [median (IQR) 7-25]. Of participating surgeons, 61% believed that evidence supported surgical AF ablation reducing the incidence of thrombo-embolic complications, and 46% modified anticoagulation decision-making based on whether they performed AF ablation. During coronary artery bypass grafting, isolated pulmonary vein isolation was the most commonly performed lesion set (70%), whereas complete left atrial ablation (46%) and biatrial ablation (44%) were favoured with valve surgery.
In a multinational group of academic surgeons, surgical AF ablation utilization appears variable, and average case volumes are low. Despite no evidence to that effect, the majority believe that ablation reduces AF-related thrombo-embolic risk of patients. Reported practice patterns suggest clinical equipoise; a definitive trial appears feasible based on respondent willingness to participate.
尽管有建议指出,对于因其他适应证而接受心脏手术的房颤患者,手术消融房颤(AF)是合理的,但该手术的临床影响仍不清楚。我们旨在描述外科医生对此类手术的操作和看法。
我们与内容和方法专家合作,设计了一份自我管理的调查问卷。我们调查了来自 18 个国家的 80 个中心的 268 名心脏外科医生。应答率为 76%(n=204/276),其中 49%来自北美,39%来自欧洲,12%来自其他地区。受访者每年进行中位数为 10 次(四分位距 4-30 次)的 AF 消融手术,考虑进行消融的房颤患者比例差异显著(中位数为 25%,四分位距 10-61%)。分别有 94%和 80%的外科医生认为症状性和无症状性患者均可从消融中获益。外科医生估计同期进行 AF 消融的主要并发症发生率为 16%(中位数[四分位距] 7-25%)。在参与调查的外科医生中,61%认为有证据支持手术消融可降低血栓栓塞并发症的发生率,46%根据是否进行 AF 消融来调整抗凝治疗决策。在冠状动脉旁路移植术中,最常进行的消融病变组合为孤立的肺静脉隔离(70%),而在瓣膜手术中,更倾向于进行完全左心房消融(46%)和双心房消融(44%)。
在一组多国家的学术外科医生中,手术消融房颤的应用似乎存在差异,且平均手术量较低。尽管没有证据表明这一点,但大多数医生认为消融可降低房颤相关的血栓栓塞风险。报告的实践模式表明存在临床不确定性;根据受访者的参与意愿,进行一项明确的试验似乎是可行的。