Lall Shelly C, Damiano Ralph J
Washington University School of Medicine, Barnes-Jewish Hospital, St. Louis, MO, USA.
J Interv Card Electrophysiol. 2007 Dec;20(3):73-82. doi: 10.1007/s10840-007-9186-x.
The introduction of ablation technology has revolutionized the surgical treatment of atrial fibrillation (AF). It has greatly simplified surgical approaches and has significantly increased the number of procedures being performed. Various energy sources have been used clinically, including cryoablation, radiofrequency, microwave, laser, and high-frequency ultrasound. The goal of these devices is to create conduction block to either block activation wavefronts or to isolate the triggers of AF. All present devices have been shown to have clinical efficacy in some patients. The devices each have their unique advantages and disadvantages. It is important that surgeons develop accurate dose-response curves for new devices in clinically relevant models on both the arrested and beating heart. This will allow the appropriate use of technology to facilitate AF surgery.
消融技术的引入彻底改变了心房颤动(AF)的外科治疗。它极大地简化了手术方法,并显著增加了手术操作的数量。临床上已使用了多种能量源,包括冷冻消融、射频、微波、激光和高频超声。这些设备的目标是形成传导阻滞,以阻断激活波前或隔离房颤的触发因素。所有现有设备在一些患者中均已显示出临床疗效。每种设备都有其独特的优缺点。外科医生在停搏心脏和跳动心脏的临床相关模型中为新设备绘制准确的剂量反应曲线非常重要。这将有助于合理使用技术以促进房颤手术。