School of Nursing, Midwifery and Paramedicine, University of the Sunshine Coast, Locked Bag 4, Maroochydore DC, QLD, 4558, Australia.
Sunshine Coast Hospital and Health Service, Maroochydore DC, Queensland, Australia.
BMC Pregnancy Childbirth. 2018 Oct 10;18(1):395. doi: 10.1186/s12884-018-2024-6.
For over 25 years cord blood has been used as an alternative to bone marrow for therapeutic use in conditions of the blood, immune system and metabolic disorders. Parents can decide if they would like to privately store their infant's cord blood for later use if needed or to publicly donate it. Parents need to be aware of the options that exist for their infant's cord blood and have access to the relevant information to inform their choice. The aim of this paper is to identify parent's knowledge and awareness of cord blood donation, private banking options and stem cell use, and parent sources and preferred sources of this information.
An integrative review was conducted using several electronic databases to identify papers on parents' knowledge, attitudes and attitudes towards umbilical cord blood donation and banking. The CASP tool was used to determine validity and quality of the studies included in the review.
The search of the international literature identified 25 papers which met review inclusion criteria. This integrative review identified parents' knowledge of cord banking and/or donation as low, with awareness of cord blood banking options greater than knowledge. Parents were found to have positive attitudes towards cord blood donation including awareness of the value of cord blood and its uses, with the option considered to be an ethical and altruistic choice. Knowledge on cord blood use were mixed; many studies' participants did not correctly identify uses. Information sources for parents on cord blood was found to be varied, fragmented and inconsistent. Health professionals were identified as the preferred source of information on cord blood banking for parents.
This integrative review has identified that further research should focus on identifying information that expectant parents require to assist them to make informed choices around cord blood banking; and identifying barriers present for health professionals providing evidence based information on cord blood use and banking options.
25 多年来，脐带血已被用作治疗血液、免疫系统和代谢紊乱疾病的骨髓替代物。父母可以决定是否要私下储存婴儿的脐带血以备将来需要，或者将其捐赠给公共库。父母需要了解他们婴儿脐带血的选择，并能够获得相关信息以做出明智的选择。本文旨在确定父母对脐带血捐献、私人银行选择和干细胞使用的知识和意识，以及父母获取这些信息的来源和偏好。
采用综合评价方法，通过多个电子数据库检索关于父母对脐带血捐献和存储的知识、态度和看法的论文。使用 CASP 工具来确定纳入研究的有效性和质量。
对国际文献的检索确定了 25 篇符合综述纳入标准的论文。这项综合评价发现，父母对脐带血存储和/或捐献的了解程度较低，对脐带血存储选择的认识程度高于知识水平。父母对脐带血捐献持有积极的态度，包括对脐带血的价值和用途的认识，认为这是一种符合伦理和利他主义的选择。关于脐带血使用的知识则参差不齐，许多研究的参与者并没有正确识别出其用途。父母获取脐带血信息的来源多种多样、分散且不一致。医疗保健专业人员被认为是父母脐带血存储方面信息的首选来源。
这项综合评价表明，未来的研究应重点关注确定准父母在脐带血存储方面做出明智决策所需的信息，并确定医疗保健专业人员在提供脐带血使用和存储选择的循证信息方面存在的障碍。
